YM-90709
目录号: A15999
interleukin-5 receptor 拮抗剂
YM-90709 是一种白细胞介素-5受体拮抗剂。YM-90709 抑制 IL-5 与其在外周人类嗜酸性粒细胞和丁酸处理的嗜酸性 HL-60 克隆 15 细胞上的受体结合,其 IC50 值分别为 1.0 和 0.57 微摩尔。
Discription | YM-90709 is an interleukin-5 receptor antagonist. YM-90709 inhibits the binding of IL-5 to its receptor on peripheral human eosinophils and butyric acid-treated eosinophilic HL-60 clone 15 cells, with IC50 values of 1.0 and 0.57 microM, respectively. | ||
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目录号 | A15999 |
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分子式 | C22H21N3O2 |
分子量 | 359.43 |
CAS号 | 163769-88-8 |
SMILES | CC(CC1=CC(OC)=C(OC)C=C12)(C)N3C2=CC4=NC5=CC=CC=C5N=C43 |
其他名称 | YM 90709, YM90709 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 42 mg/mL (116.85 mM) | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 27.82 mL | 139.11 mL | 278.22 mL |
0.5 mM | 5.56 mL | 27.82 mL | 55.64 mL |
1 mM | 2.78 mL | 13.91 mL | 27.82 mL |
5 mM | 0.56 mL | 2.78 mL | 5.56 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2