YM155 (Sepantronium Bromide)

Name: YM155 (Sepantronium Bromide)
SKU: A11002
Price: 175 CNY
Rating: 5 (13 reviews)

目录号: A11002

Survivin 抑制剂

13 篇发表文献

YM155 是一种新型小分子 survivin 抑制剂，其对 survivin 启动子活性的抑制 IC50 为 0.54 nM。

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Grouped product items
规格	价格	库存
2mg	¥175.00	现货
5mg	¥245.00	现货
10mg	¥455.00	现货
25mg	¥1,015.00	现货
50mg	¥1,855.00	现货
100mg	¥2,765.00	现货
500mg	¥6,825.00	现货
*10mM 1mL in DMSO**	¥350.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

Other Forms of YM155 (Sepantronium Bromide)

YM-155 HCl (Sepantronium HCl)

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用YM155 (Sepantronium Bromide)发表的13篇文献

Atieh Pourbagheri-Sigaroodi, .et al. , Iran J Allergy Asthma Immunol, 2024, 23(6):699-726

Bopei Cui, .et al. , Signal Transduct Target Ther, 2023, Sep 25;8(1):366 PMID: 37743418

Ali Nasrollahzadeh, .et al. , Biochim Biophys Acta Mol Cell Res, 2021, Jun 26;1868(10):119087 PMID: 34182011

Chia-Hui Huang, .et al. , Toxicol Appl Pharmacol, 2020, Apr 17;397:115013 PMID: 32305283

Turner TH, .et al. , Sci Rep, 2020, Jan 30;10(1):1493 PMID: 32001757

Chiou JT, .et al. , Toxicol Appl Pharmacol, 2019, Dec 16;387:114857 PMID: 31837377

Hamzehlou S, .et al. , Eur J Pharmacol, 2019, Nov 15;863:172705 PMID: 31574259

Momeny M, .et al. , Cell Oncol (Dordr), 2019, Apr 25 PMID: 31025257

Yamamoto M, .et al. , Anticancer Res, 2019, Feb;39(2):609-617 PMID: 30711936

V??zquez-Mellado MJ, .et al. , Oncol Rep, 2018, Nov 27 PMID: 30483799

MASAHIRO YAMAMOTO, .et al. , Anticancer Res, 2018, Dec 38 (12) 6699-6706 PMID: 30504379

Ahn MR, .et al. , Drug Discov Ther, 2017, 11(6):300-306 PMID: 29332887

MASAYA MINODA, .et al. , Int J Oncol, 2015, Sep; 47(3): 891-899 PMID: 26166250

生物活性

Discription

YM155 is a novel small molecule survivin suppressant with an IC50 of 0.54 nM for the inhibition of survivin promoter activity.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A11002
分子式	C20H19BrN4O3
分子量	443.3
CAS号	781661-94-7
SMILES	CC1=[N+](C2=C(N1CCOC)C(=O)C3=CC=CC=C3C2=O)CC4=NC=CN=C4.[Br-]
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	52 mg/mL (117.3 mM)
	Water	85 mg/mL (191.75 mM)
	Ethanol	6 mg/mL (13.53 mM)
In vivo	Saline	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.56 mL	112.79 mL	225.58 mL
0.5 mM	4.51 mL	22.56 mL	45.12 mL
1 mM	2.26 mL	11.28 mL	22.56 mL
5 mM	0.45 mL	2.26 mL	4.51 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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