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YZ129 is an inhibitor of the HSP90-calcineurin-NFAT pathway against glioblastoma, directly binding to heat shock protein 90 (HSP90) with an IC50 of 820 nM on NFAT nuclear translocation.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 33.3 mL | 166.49 mL | 332.99 mL |
| 0.5 mM | 6.66 mL | 33.3 mL | 66.6 mL |
| 1 mM | 3.33 mL | 16.65 mL | 33.3 mL |
| 5 mM | 0.67 mL | 3.33 mL | 6.66 mL |
*The above data is based on the productmolecular weight 300.31. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A13601 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 300.31 |
| Formula | C19H12N2O2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1643120-60-8 |
| Synonyms | YZ 129, YZ-129 |
| SMILES | O=C(C1=CC=CC=C1C(NC2=CC=C(C=NC=C3)C3=C2)=C4)C4=O |
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