YZ129

Name: YZ129
SKU: A13601

目录号: A13601

HSP90-calcineurin-NFAT inhibitor

YZ129 Chemical Structure

CAS NO. 1643120-60-8

YZ129 is an inhibitor of the HSP90-calcineurin-NFAT pathway against glioblastoma, directly binding to heat shock protein 90 (HSP90) with an IC50 of 820 nM on NFAT nuclear translocation.

库存：现货

规格	价格	数量
1 mg	￥ 2,240.00
5 mg	￥ 6,720.00
10 mg	￥ 11,200.00

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生物活性

YZ129 is an inhibitor of the HSP90-calcineurin-NFAT pathway against glioblastoma, directly binding to heat shock protein 90 (HSP90) with an IC50 of 820 nM on NFAT nuclear translocation.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	33.3 mL	166.49 mL	332.99 mL
0.5 mM	6.66 mL	33.3 mL	66.6 mL
1 mM	3.33 mL	16.65 mL	33.3 mL
5 mM	0.67 mL	3.33 mL	6.66 mL

*The above data is based on the productmolecular weight 300.31. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A13601
作用机制	Inhibitor (抑制剂)
M. Wt	300.31
Formula	C19H12N2O2
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1643120-60-8
Synonyms	YZ 129, YZ-129
SMILES	O=C(C1=CC=CC=C1C(NC2=CC=C(C=NC=C3)C3=C2)=C4)C4=O