ZL0420
目录号: A16829
BRD4 inhibitor
ZL0420 是一种强效且选择性的 BRD4 抑制剂,其对 BRD4 BD1 的 IC50 值为 27 nM,对 BRD4 BD2 的 IC50 值为 32 nM,且相对于相关的 BRD2 同源体具有良好的选择性。
Discription | ZL0420 is a potent and selective BRD4 inhibitor with IC50 values of 27 nM against BRD4 BD1 and 32 nM against BRD4 BD2 respectively and good selectivity over that of the related BRD2 homolog. |
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目录号 | A16829 |
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分子式 | C16H16N4O2 |
分子量 | 296.32 |
CAS号 | 2229039-45-4 |
SMILES | CC1=C(O)C=C(N)C(/N=N/C2=CC(CCC(N3)=O)=C3C=C2)=C1 |
其他名称 | ZL 0420, ZL-0420 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 58 mg/mL (195.73 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 33.75 mL | 168.74 mL | 337.47 mL |
0.5 mM | 6.75 mL | 33.75 mL | 67.49 mL |
1 mM | 3.37 mL | 16.87 mL | 33.75 mL |
5 mM | 0.67 mL | 3.37 mL | 6.75 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2