ZM 336372
目录号: A11077
C-Raf 抑制剂
ZM 336372 是一种强效的 ATP-竞争性 Raf-1 抑制剂（体外 IC50 = 70 nM），具有在整个细胞中诱导 Raf-1 活性增强超过100倍的矛盾效应。
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生物活性
| Discription | ZM 336372 is a potent ATP-competitive inhibitor of Raf-1 in vitro (IC50 = 70 nM) with the paradoxical effect of inducing >100-fold activation of Raf-1 in whole cells. | ||
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产品信息
| 目录号 | A11077 |
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| 分子式 | C23H23N3O3 |
| 分子量 | 389.5 |
| CAS号 | 208260-29-1 |
| SMILES | CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC=C2)N(C)C)NC(=O)C3=CC=C(C=C3)O |
| 其他名称 | ZM-336372, ZM336372 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 75 mg/mL (192.58 mM) | |
| Water | Insoluble | ||
| Ethanol | 2 mg/mL (5.13 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.67 mL | 128.37 mL | 256.74 mL |
| 0.5 mM | 5.13 mL | 25.67 mL | 51.35 mL |
| 1 mM | 2.57 mL | 12.84 mL | 25.67 mL |
| 5 mM | 0.51 mL | 2.57 mL | 5.13 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 208260-29-1 | 208260-29-1 供应商 | 208260-29-1 花费 | 208260-29-1 生产商 | 订购 208260-29-1 | 208260-29-1 代理商