ZM 39923 HCl
目录号: A13509
JAK3 抑制剂
ZM 39923 HCl 是一种 JAK3 抑制剂(IC50 = 79 nM),对表皮生长因子受体、JAK1 和 细胞周期依赖性激酶4 的抑制作用较弱(IC50 分别为 2.4 µM、40 µM 和 10 µM)。
Discription | ZM 39923 HCl is an inhibitor of JAK3 (IC50 = 79 nM) that less potently inhibits epidermal growth factor receptor, JAK1, and cyclin-dependent kinase 4 (IC50s = 2.4, 40, and 10 M, respectively) | ||
---|---|---|---|
Targets |
|
目录号 | A13509 |
---|---|
分子式 | C23H25NOHCl |
分子量 | 367.9 |
CAS号 | 1021868-92-7 |
SMILES | O=C(CCN(CC1=CC=CC=C1)C(C)C)C2=CC3=CC=CC=C3C=C2.Cl |
其他名称 | JAK3 Inhibitor IV |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 26 mg/mL (70.67 mM) | |
Water | Insoluble | ||
Ethanol | 7 mg/mL (19.02 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 27.18 mL | 135.91 mL | 271.81 mL |
0.5 mM | 5.44 mL | 27.18 mL | 54.36 mL |
1 mM | 2.72 mL | 13.59 mL | 27.18 mL |
5 mM | 0.54 mL | 2.72 mL | 5.44 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2