Zotarolimus

Name: Zotarolimus
SKU: A11950

目录号: A11950

mTOR 抑制剂

Zotarolimus Chemical Structure

CAS NO. 221877-54-9

Zotarolimus是一种免疫抑制剂，可以抑制FKBP-12结合的IC50为2.8nM。。它是雷帕霉素的半合成衍生物。它设计用于以磷酸胆碱为载体的支架。

库存：现货

规格	价格	数量
2 mg	￥ 770.00
5 mg	￥ 1,050.00
10 mg	￥ 1,680.00
25 mg	￥ 2,940.00
10mM * 1mL in DMSO	￥ 1,750.00

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生物活性

Zotarolimus是一种免疫抑制剂，可以抑制FKBP-12结合的IC50为2.8nM。。它是雷帕霉素的半合成衍生物。它设计用于以磷酸胆碱为载体的支架。

靶点信息

FKBP-12
2.8 nM

溶解度 *

In vitro	DMSO	89 mg/mL (92.11 mM)
	Water	Insoluble
	Ethanol	89 mg/mL (92.11 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	10.35 mL	51.75 mL	103.5 mL
0.5 mM	2.07 mL	10.35 mL	20.7 mL
1 mM	1.03 mL	5.17 mL	10.35 mL
5 mM	0.21 mL	1.03 mL	2.07 mL

*The above data is based on the productmolecular weight 966.21. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A11950
作用机制	Inhibitor (抑制剂)
M. Wt	966.21
Formula	C52H79N5O12
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	221877-54-9
Synonyms	A 179578, ABT 578, Resolute, 42-(1-Tetrazolyl)rapamycin
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