ZXH-3-26

Name: ZXH-3-26
SKU: A18399

目录号: A18399

PROTAC BRD4 degrader

ZXH-3-26 Chemical Structure

CAS NO. 2243076-67-5

ZXH-3-26 is a selective PROTAC BRD4 degrader with a DC50/5h (DC50/5h referring to half-maximal degradation after 5 hours of treatment) of ~ 5 nM.

库存：现货

规格	价格	数量
5 mg	￥ 1,960.00
10 mg	￥ 3,640.00
50 mg	￥ 12,460.00
100 mg	￥ 18,760.00

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生物活性

ZXH-3-26 is a selective PROTAC BRD4 degrader with a DC50/5h (DC50/5h referring to half-maximal degradation after 5 hours of treatment) of ~ 5 nM.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	12.73 mL	63.67 mL	127.34 mL
0.5 mM	2.55 mL	12.73 mL	25.47 mL
1 mM	1.27 mL	6.37 mL	12.73 mL
5 mM	0.25 mL	1.27 mL	2.55 mL

*The above data is based on the productmolecular weight 785.27. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A18399
作用机制	Degrader (降解剂)
M. Wt	785.27
Formula	C38H37ClN8O7S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	2243076-67-5
Synonyms	ZXH326, ZXH-326
SMILES	O=C(OC)C[C@H]1C2=NN=C(C)N2C3=C(C(C)=C(C(NCCCCCNC4=CC=CC(C(N5C(CC6)C(NC6=O)=O)=O)=C4C5=O)=O)S3)C(C7=CC=C(Cl)C=C7)=N1