c-Ret

Inhibitory Selectivity

Catalog No.	Inhibitor Name	c-RET	Other
A10250	Regorafenib	****	Raf-1,VEGFR2,Kit
A10715	Danusertib	**	Aurora A,Abl,TrkA
A11180	TG101209	***	JAK2,FLT3,JAK3
A13832	RPI-1	*

Notes:
1.Hover mouse over " * " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " * " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.

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Regorafenib monohydrate

Catalog No. A15218
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Tyrosine kinase 抑制剂

Regorafenib monohydrate是VEGFR1/VEGFR2/VEGFR3/PDGFRβ/Kit/RET和Raf-1的多靶点抑制剂，IC50分别为13 nM/4.2 nM/46 nM/22 nM/7 nM/1.5 nM和2.5 nM。了解更多

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