CETP

Inhibitory Selectivity

Catalog No.	Inhibitor Name	CETP
A11084	Anacetrapib (MK-0859)	***
A11242	Torcetrapib (CP-529414)	**
A11213	JTT-705 (Dalcetrapib)	*
A11397	Evacetrapib (LY2484595)	****

Notes:
1.Hover mouse over " * " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " * " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.

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CKD-519

Catalog No. A18873
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CETP inhibitor

CKD-519 is a selective and potent cholesteryl ester transfer protein (CETP) inhibitor being developed for the treatment of dyslipidemia to raise high-density lipoprotein cholesterol. Single doses of CKD-519 up to 400 mg were well tolerated and showed potent inhibition of CETP activity. 了解更多

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CETP-IN-3

Catalog No. A18878
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CETP inhibitor

CETP-IN-3 (Compound 13) is an small molecule inhibitor of the plasma glycoprotein cholesterol ester transfer protein (CETP), elevating HDL-C through inhibition of CETP. 了解更多

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Anacetrapib (MK-0859)

Catalog No. A11084
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CETP 抑制剂

Anacetrapib (MK-0859)是一种有效的，选择性，可逆的rhCETP和突变CETP(C13S)抑制剂，IC50分别为7.9 nM和11.8 nM，提高HDL-C，降低LDL-C，不提高醛固酮和血压。了解更多

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JTT-705 (Dalcetrapib)

Catalog No. A11213
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CETP 抑制剂

JTT-705 (Dalcetrapib)是一种CETP抑制剂，抑制CETP是增加HDL-胆固醇并可能减少动脉粥样硬化的目标。了解更多

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Torcetrapib (CP-529414)

Catalog No. A11242
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CETP 抑制剂

Torcetrapib (CP-529414)是一种CETP抑制剂，IC50为37 nM。了解更多

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Evacetrapib (LY2484595)

Catalog No. A11397
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CETP 抑制剂

Evacetrapib (LY2484595)是一种强效选择性CETP抑制剂，IC50为5.5 nM，可在不增加醛固酮或血压的情况下升高HDL胆固醇。了解更多

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