MMP
Catalog No. | Inhibitor Name | MMP |
---|---|---|
A12985 | Batimastat (BB-94) | *** |
A13320 | Ilomastat (GM6001, Galardin) | **** |
A14253 | SB-3CT | * |
A12826 | Marimastat (BB-2516) | *** |
A13072 | NSC 405020 | |
A10651 | Nobiletin |
Notes:
1.Hover mouse over " " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.
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Abametapir
Catalog No. A15945 metalloproteinase 抑制剂ABAMETAPIR是Xeglyze乳液的活性成分。ABAMETAPIR抑制金属蛋白酶;对卵子发育,若虫和成年虱子存活至关重要的生理过程必不可少的酶。 了解更多 -
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最新产品
Incyclinide
Catalog No. A17240 MMP inhibitorIincyclinide, also known as CMT-3 and COL-3, is a MMP inhibitor and a chemically-modified tetracycline with potential antineoplastic activity. Incyclinide inhibits matrix metalloproteinases (MMPs), thereby inducing extracellular matrix degradation, and inhibiting angiogenesis, tumor growth and invasion, and metastasis. This agent also causes mitochondrial depolarization in tumor cells and induces both cellular apoptosis and tissue necrosis. 了解更多 -
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TAPI-0
Catalog No. A13724 -
Batimastat (BB-94)
Catalog No. A12985 MMP 抑制剂Batimastat (BB-94)是多种基质金属蛋白酶(MMP)的强效合成抑制剂,包括间质胶原酶(IC50 = 3 nM),溶血素(IC50 = 20 nM),Mr 72,000型IV胶原酶(IC50 = 4) nM),92,000型IV胶原酶先生(IC50 = 4 nM)和基质溶素(IC50 = 6 nM)。它是一种低分子量(MW = 478)的肽样胶原蛋白底物类似物,由类似物结合而成,分别与MMP和催化活性锌原子结合在一起。 了解更多 -
CTS-1027
Catalog No. A11345 -
Doxycycline monohydrate
Catalog No. A17813 MMP inhibitorDoxycycline monohydrate is an antibiotic and broad-spectrum metalloproteinase (MMP) inhibitor. 了解更多 -
Doxycycline
Catalog No. A17545 MMP inhibitorDoxycycline, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor. 了解更多 -
Apratastat
Catalog No. A13330 dual TACE/MMPs inhibitorApratastat is an orally active, potent, and reversible dual inhibitor of tumor necrosis factor-α converting enzyme (TACE) and matrix metalloproteinases (MMPs) . 了解更多 -
MMP3 inhibitor 1
Catalog No. A13185 MMP-3 inhibitorMMP3 inhibitor 1 is a potent and highly selective MMP-3 inhibitor with an IC50 of 1 nM. 了解更多 -
20(R)-Ginsenoside Rh2
Catalog No. A15408 -
Batimastat sodium salt
Catalog No. A15326 MMP 抑制剂Batimastat sodium salt是一种抗癌药物,属于称为血管生成抑制剂的药物家族。Batimastat(BB-94)是一种有效的广谱基质金属蛋白酶(MMP)抑制剂。 了解更多 -
UK 370106
Catalog No. A15316 -
ARP 101
Catalog No. A15293 -
CL-82198
Catalog No. A13597 -
SB-3CT
Catalog No. A14253 -
GM 6001
Catalog No. A13320 -
Marimastat
Catalog No. A12826 -
NSC 405020
Catalog No. A13072 MT1-MMP 抑制剂NSC-405020是一种膜1型基质金属蛋白酶(MT1-MMP)抑制剂(IC50> 100μmol/ L)。 了解更多 -
4-epi-Chlortetracycline Hydrochloride
Catalog No. A12848 MMP 抑制剂4-epi-Chlortetracycline Hydrochloride是一种四环素衍生物,可作为金属蛋白酶(MMP)抑制剂,用于治疗组织破坏性疾病和癌症。 了解更多