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| Catalog No. | Inhibitor Name | Syk | Other |
|---|---|---|---|
| A10769 | R406 besylate | ** | Flt3 |
| A10770 | R406 (Tamatinib) | ** | Flt3 |
| A10771 | R788 Disodium | ** | |
| A12731 | PRT062607 HCl | **** | FGR,MLK1,YES |
| A11926 | Fostamatinib | ** | Adenosine A3 receptor,Adenosine transporter,Monoamine transporter |
| A16240 | MNS | * | p97,Src |
| A15524 | PRT-060318 | **** | |
| A13884 | Entospletinib | *** | |
| A11320 | BAY-61-3606 | *** | |
| A12162 | Piceatannol | Lyn,PKA,PKC | |
| A11952 | P505-15 (PRT062607, BIIB057) | **** | FGR, MLK1 |
| A14161 | R112 | * |
Notes:
1.Hover mouse over "" to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of "" is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.
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PRT 062070 (Cerdulatinib)
Catalog No. A14147 Dual Syk and JAK 抑制剂PRT 062070 (Cerdulatinib)是一种新型的口服双脾酪氨酸激酶（Syk）和janus激酶（JAK）抑制剂。Cerdulatinib优先抑制各种细胞类型中JAK1和JAK3依赖性细胞因子介导的信号传导和功能性反应。 了解更多 -
R406 besylate
Catalog No. A10769 Syk 抑制剂R406 besylate是一种口服酪氨酸激酶抑制剂，IC50为41 nM。对Syk抑制作用强，但是不抑制Lyn，对Flt3的作用比对Syk低5倍。 了解更多
2 个项目
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