TNF-α
Catalog No. | Inhibitor Name | TNF-α | Other |
---|---|---|---|
A10743 | Pomalidomide | *** | |
A11973 | Necrostatin-1 | * | |
A12748 | QNZ | **** | NF-κB |
A10924 | Thalidomide | ||
A10522 | Lenalidomide (CC-5013) | *** |
Notes:
1.Hover mouse over " " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.
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QNZ (EVP4593)
Catalog No. A12748 -
Pomalidomide (CC-4047)
Catalog No. A10743 TNF-alpha 抑制剂Pomalidomide (CC-4047)是沙利度胺的衍生物,在PBMCs中IC50为13 nM,并起免疫调节剂的作用。 了解更多 -
Necrostatin-1
Catalog No. A11973 RIPK1 抑制剂Necrostatin-1是一种与ATP竞争的,与受体相互作用的蛋白激酶1(RIPK1)的变构抑制剂(EC50 = 182 nM)。 了解更多 -
GW 4869
Catalog No. A11974 -
Necrostatin 2
Catalog No. A15183 -
Necrostatin 2 racemate
Catalog No. A15327 -
Necrostatin 2 S enantiomer
Catalog No. A15328 -
Thalidomide
Catalog No. A10924