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￥ 0.00 TNF-α
| Catalog No. | Inhibitor Name | TNF-α | Other |
|---|---|---|---|
| A10743 | Pomalidomide | *** | |
| A11973 | Necrostatin-1 | * | |
| A12748 | QNZ | **** | NF-κB |
| A10924 | Thalidomide | ||
| A10522 | Lenalidomide (CC-5013) | *** |
Notes:
1.Hover mouse over "" to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of "" is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.
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Lenalidomide (CC-5013)
Catalog No. A10522 Ubiquitin ligase inducerLenalidomide (CC-5013)是Thalidomide的衍生物。在体外，Lenalidomide具有三种主要活性:直接抗肿瘤作用、抑制肿瘤细胞的微环境支持和免疫调节作用。它通过抑制骨髓基质细胞支持、抗血管生成和抗破骨细胞生成作用以及免疫调节活性直接和间接诱导肿瘤细胞凋亡。 了解更多
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