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￥ 0.00 DPP-4
| Catalog No. | Inhibitor Name | DPP-4 |
|---|---|---|
| A10848 | Sitagliptin phosphate monohydrate | ** |
| A11224 | Linagliptin | **** |
| A12528 | Vildagliptin (LAF-237) | *** |
| A11109 | Saxagliptin | * |
| A13571 | Alogliptin | *** |
| A14293 | Trelagliptin |
Notes:
1.Hover mouse over "" to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of "" is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.
29 个项目
每页
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Vildagliptin dihydrate
Catalog No. A21898 DPP4 inhibitorVildagliptin (LAF237 dihydrate;NVP-LAF 237 dihydrate) is a dipeptidyl peptidase 4 (DPP4) inhibitor that delays the degradation of glucagon-like peptide-1 (GLP-1). 了解更多 -
Dutogliptin
Catalog No. A21573 DPP4 inhibitorDutogliptin (PHX-1149 free base) is an orally available, potent, and selective dipeptidyl peptidase-4 (DPP4) inhibitor for the treatment of type 2 diabetes mellitus. 了解更多 -
Gosogliptin
Catalog No. A21566 DPP-IV inhibitorGosogliptin is a potent and selective inhibitor of dipeptidyl peptidase-IV (DPP-IV). 了解更多 -
Diprotin A TFA
Catalog No. A21475 DPP IV inhibitorDiprotin A (TFA) is an inhibitor of dipeptidyl peptidase IV (DPP-IV). 了解更多 -
Teneligliptin hydrobromide hydrate
Catalog No. A21465 DPP-4 inhibitorTeneligliptin hydrobromide hydrate is a potent chemotype prolylthiazolidine-based DPP-4 inhibitor, which competitively inhibits human plasma, rat plasma, and human recombinant DPP-4 in vitro, with IC50s of approximately 1 nM. 了解更多 -
Gemigliptin
Catalog No. A21285 DPP4 inhibitorGemigliptin is a highly selective dipeptidyl peptidase 4 (DPP4) inhibitor with a KD of 7.25 nM. 了解更多 -
Saxagliptin hydrate
Catalog No. A16694 DPP4 inhibitorSaxagliptin H2O(BMS477118 H2O) is a selective and reversible DPP4 inhibitor with IC50 of 26 nM and Ki of 1.3 nM. 了解更多 -
Talabostat
Catalog No. A14079 DPP-IV inhibitorTalabostat (Val-boroPro; PT100) is an orally active and nonselective dipeptidyl peptidase IV (DPP-IV) inhibitor (IC50 < 4 nM; Ki = 0.18 nM) and the first clinical inhibitor of fibroblast activation protein (FAP) (IC50 = 560 nM). 了解更多 -
1G244
Catalog No. A18709 -
Teneligliptin
Catalog No. A15505 -
NVP DPP 728 dihydrochloride
Catalog No. A15320 DPP-4 抑制剂NVP DPP 728 dihydrochloride是一种有效的活性二肽基肽酶(DPP)-IV抑制剂，Ki和IC50值分别为11 nM和14 nM。 了解更多 -
PK 44 phosphate
Catalog No. A15309 -
DPPI 1c hydrochloride
Catalog No. A15298 DPP-4 抑制剂DPPI 1c hydrochloride是一种双氰基吡咯烷化合物，可作为CD26（DPP 4）的缓慢结合和定点活性抑制剂，IC50 = 106 nM，对DPP II，DPP III，DPP VIII，DPP IX，FAP几乎没有活性，甚至浓度高达30μM的APP。 了解更多 -
Teneligliptin hydrobromide
Catalog No. A15258 DPP-4 抑制剂Teneligliptin hydrobromide是一种新颖，有效且持久的二肽基肽酶-4抑制剂。在体外竞争性抑制人血浆，大鼠血浆和人重组DPP-4，IC50值约为1 nM。 了解更多 -
UAMC 00039 dihydrochloride
Catalog No. A16047 DPP-II 抑制剂UAMC 00039 dihydrochloride是二肽基肽酶II（DPP-II）的有效抑制剂（IC50 = 0.48 nM）。展示了DPP-II对DPP-9，DPP-8和DPP-IV的选择性（IC50值分别为78.6、142和165μM）。 了解更多 -
Talabostat mesylate
Catalog No. A14080 -
Anagliptin
Catalog No. A13529 -
Alogliptin
Catalog No. A13571 -
Sitagliptin
Catalog No. A14377 -
Trelagliptin Succinate (SYR-472)
Catalog No. A13312 DPP-4 抑制剂Trelagliptin Succinate (SYR-472)是一种长效的二肽基肽酶4（DPP-4）抑制剂，正在开发用于治疗2型糖尿病（T2D）。 了解更多 -
Alogliptin Benzoate
Catalog No. A13311 -
Vildagliptin
Catalog No. A12528 -
Linagliptin (BI-1356)
Catalog No. A11224 DPP-4 抑制剂Linagliptin (BI-1356)是DPP-4抑制剂，是一种降解肠降血糖素激素胰高血糖素样肽1（GLP-1）和葡萄糖依赖性促胰岛素多肽（GIP）的酶。 了解更多 -
Sitagliptin phosphate monohydrate
Catalog No. A10848 DDP-4 抑制剂Sitagliptin phosphate monohydrate是二肽基肽酶-4（DPP-4）类的抗糖尿病（抗高血糖）药物。 DPP-4酶的抑制作用被认为会增加胰高血糖素样肽1（GLP-1），从而抑制胰高血糖素释放，刺激胰岛素释放并降低血糖。 了解更多 -
Saxagliptin (BMS-477118)
Catalog No. A11109 DPP-4 抑制剂Saxagliptin (BMS-477118)是一种新型二肽基肽酶4（DPP-4）抑制剂，IC50为50 nM。 了解更多
29 个项目
每页