MDM2
Catalog No. | Inhibitor Name | Mdm2 | Other |
---|---|---|---|
A10657 | Nutlin-3 | ** | |
A11501 | Nutlin-3a | *** | |
A11502 | Nutlin-3b | * | |
A16348 | MX69 | ** | |
A15440 | MI-773 (SAR405838) | **** | p53 |
A14211 | Idasanutlin (RG-7388) | **** | |
A11523 | RG-7112 | *** | |
A14118 | YH239-EE |
Notes:
1.Hover mouse over " " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.
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p53 and MDM2 proteins-interaction-inhibitor racemic
Catalog No. A15202 -
Idasanutlin (RG7388)
Catalog No. A14211 -
p53 and MDM2 proteins-interaction-inhibitor chiral
Catalog No. A15201 -
NVP-CGM097
Catalog No. A16326 -
MDM2 Inhibitor
Catalog No. A13582 -
RG7112
Catalog No. A11523 -
MI-773 (SAR405838)
Catalog No. A14423 Mdm2 抑制剂MI-773 (SAR405838)是一种新的MDM2-p53相互作用的小分子抑制剂,以高亲和力(Ki = 0.88 nM)结合MDM2,并阻断p53-MDM2相互作用。 了解更多