MDM2

Inhibitory Selectivity

Catalog No.	Inhibitor Name	Mdm2	Other
A10657	Nutlin-3	**
A11501	Nutlin-3a	***
A11502	Nutlin-3b	*
A16348	MX69	**
A15440	MI-773 (SAR405838)	****	p53
A14211	Idasanutlin (RG-7388)	****
A11523	RG-7112	***
A14118	YH239-EE

Notes:
1.Hover mouse over " * " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " * " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.

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p53 and MDM2 proteins-interaction-inhibitor racemic

Catalog No. A15202
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p53-MDM2 interaction 抑制剂

p53和MDM2蛋白相互作用抑制剂消旋体是p53和MDM2蛋白之间相互作用的抑制剂。了解更多

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WR 1065

Catalog No. A15353
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P53/p21waf-1/MDM2 activator

WR 1065是一种氨磷汀（Ethyol）的去磷酸化代谢产物，可防止受到辐射的直接和延迟影响。了解更多

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p53 and MDM2 proteins-interaction-inhibitor chiral

Catalog No. A15201
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p53-MDM2 interaction 抑制剂

p53和MDM2蛋白相互作用抑制剂手性是p53和MDM2蛋白之间相互作用的抑制剂。了解更多

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Idasanutlin (RG7388)

Catalog No. A14211
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MDM2/p53 抑制剂

Idasanutlin (RG7388)是一种有效的选择性p53-MDM2抑制剂。了解更多

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Kevetrin HCl

Catalog No. A13797
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Kevetrin (thioureidobutyronitrile)是一种水溶性小分子，是肿瘤抑制蛋白p53的激活剂，具有潜在的抗肿瘤活性。了解更多

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RG7112

Catalog No. A11523
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selective p53-MDM2 抑制剂

RG7112是首个临床小分子MDM2抑制剂，HTRF IC50为18 nM，设计用于占据MDM2的p53结合口袋。了解更多

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