Stat

Catalog No.Inhibitor Name STAT1STAT3STAT5Other
A10817S3I-201
*
A12733Stattic
**
A14249SH-4-54
****
****
A10244Cryptotanshinone
**
A10396Fludarabine
A16220Nifuroxazide
A13474Napabucasin
A15363Cucurbitacin I
JAK2
A15364SD 1008
JAK2
A15366ZM 449829
JAK3, EGFR, JAK1, CDK4
A15729Corylifol A
*
A15885HO-3867
A10087Artesunate
EXP1(a membrane glutathione S-transferase)

Notes:
1.Hover mouse over " * " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " * " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.

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  1. Cucurbitacin I

    Catalog No. A15363
    JAK2/STAT3 抑制剂
    Cucurbitacin I(Cucumis sativus L.)可以抑制v-Src转化的NIH 3T3细胞中的磷酸酪氨酸Stat3(信号转导和转录激活因子3)水平。 了解更多
  2. SD 1008

    Catalog No. A15364
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    JAK2/STAT3 抑制剂
    SD 1008是JAK2/STAT3信号通路抑制剂,可额外抑制Src。注意到SD 1008可诱导表达组成性活性酪氨酸磷酸化STAT3的细胞系凋亡。 了解更多
  3. STAT3-IN-3

    Catalog No. A18479
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    STAT3 inhibitor
    STAT3-IN-3 is a potent and selective inhibitor of signal transducer and activator of transcription 3 (STAT3). 了解更多
  4. HJC0152

    Catalog No. A16806
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    STAT3 抑制剂
    HJC0152是一种STAT3抑制剂,具有显着改善的水溶性。 了解更多
  5. STAT3-IN-1

    Catalog No. A12232
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    STAT3 inhibitor
    STAT3-IN-1 (compound 7d) is an excellent, selective and orally active STAT3 inhibitor, with IC50 values of 1.82 μM and 2.14 μM in HT29 and MDA-MB 231 cells, respectively. STAT3-IN-1 (compound 7d) induces tumor apoptosis. 了解更多
  6. C188-9

    Catalog No. A16804
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    STAT3 抑制剂
    C188-9是一种有效的STAT3抑制剂,它以高亲和力(KD = 4.7±0.4 nM)与STAT3结合。C188-9在小鼠中具有良好的耐受性,显示出良好的口服生物利用度,并且集中在肿瘤中。 了解更多

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