β-Amyloid

Inhibitory Selectivity

Catalog No.	Inhibitor Name	Beta Amyloid	Other
A10288	DAPT (GSI-IX)	**
A10802	RO4929097	***	γ secretase,γ secretase(ICN)
A11194	MK-0752	***
A10157	Avagacestat	****
A11776	LY2811376	*	BACE1

Notes:
1.Hover mouse over " * " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " * " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.

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ARN2966

Catalog No. A21016
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APP expression modulator

ARN2966 is a potent post-transcriptional modulator of APP expression; reduces expression of APP with resultant lower production of Aβ. 了解更多

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