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￥ 0.00 COX
| Catalog No. | Inhibitor Name | COX | COX-1 | COX-2 | Other |
|---|---|---|---|---|---|
| A10193 | Celecoxib | **** | |||
| A10461 | Ibuprofen | * | * | ||
| A10474 | Indomethacin | ** | * | ||
| A11918 | Rofecoxib | **** | |||
| A10304 | Diclofenac Sodium | *** | *** | ||
| A11695 | Lornoxicam | **** | **** | ||
| A10623 | Naproxen Sodium | * | * | ||
| A13342 | Valdecoxib | **** | |||
| A11693 | Tolfenamic Acid | *** | |||
| A16399 | Amfenac Sodium Monohydrate | ** | *** | ||
| A11694 | Nimesulide | * | |||
| A12520 | Meclofenamate Sodium | **** | *** | ||
| A16428 | Carprofen | **** | |||
| A10636 | Nepafenac | ||||
| A10878 | Sulindac | ||||
| A10565 | Meloxicam | ||||
| A10820 | Aspirin | ||||
| A11906 | Phenacetin | ||||
| A10736 | Piroxicam | ||||
| A10462 | Ibuprofen Lysine | ||||
| A11641 | Pranoprofen | ||||
| A10090 | Asaraldehyde | ||||
| A11692 | Acemetacin | ||||
| A13244 | Bromfenac Sodium |
Notes:
1.Hover mouse over "" to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of "" is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.
23 个项目
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Carprofen
Catalog No. A16428 -
Asaraldehyde (Asaronaldehyde)
Catalog No. A10090 -
Diclofenac sodium
Catalog No. A10304 COX 抑制剂Diclofenac Sodium是一种非选择性的COX抑制剂，完整细胞中的COX-1和-2的IC50分别为0.5μg/ml和0.5μg/ml，作用于绵羊COX-1和COX-2， IC50分别为60和220 nM，用作非甾体类抗炎药（NSAID）来减轻疼痛和减轻疼痛 肿胀发炎。 了解更多 -
FK 3311
Catalog No. A13332 -
Nimesulide
Catalog No. A11694 -
Piroxicam (Feldene)
Catalog No. A10736 -
Celecoxib
Catalog No. A10193 -
Rofecoxib (Vioxx)
Catalog No. A11918 -
Iguratimod (T 614)
Catalog No. A11464 COX-2 抑制剂Iguratimod (T 614)是一种抗风湿剂，能够有效地抑制COX-2的活性，IC50值为20 μM (7.7 μg/mL)，而对 COX-1 无作用；Iguratimod同时为巨噬细胞移动抑制因子 (MIF) 抑制剂，IC50值为6.81 μM。 了解更多 -
Valdecoxib
Catalog No. A13342 COX-2 抑制剂伐地考昔（Valdecoxib），也称为SC-65872，是一种非甾体类抗炎药（NSAID），用于治疗骨关节炎，类风湿性关节炎以及痛经和月经症状。 它是一种选择性的环氧合酶2（COX-2)抑制剂,IC50为5nM。 了解更多 -
Lornoxicam (Xefo)
Catalog No. A11695 COX 抑制剂Lornoxicam (Xefo)是一种非甾体类COX-1/COX-2抑制剂。它是oxicam类的非甾体类抗炎药（NSAID），具有镇痛（缓解疼痛），抗炎和退烧（退烧）特性。 了解更多 -
Bromfenac sodium
Catalog No. A13244 -
Tolfenamic acid
Catalog No. A11693 COX-2 抑制剂Tolfenamic Acid是一种COX-2抑制剂，IC50为0.2μM。它是非甾体抗炎药（NSAID）的一类。它用于治疗偏头痛的症状。 了解更多 -
Indomethacin (Indocid, Indocin)
Catalog No. A10474 COX 抑制剂Indomethacin (Indocid, Indocin)是一种非选择性COX1和COX2抑制剂，IC50分别为0.1 μg/mL和5 μg/mL。吲哚美辛(吲哚满，吲哚满)是一种非甾体抗炎药，通常用于减轻发热、疼痛、僵硬和肿胀。 了解更多 -
Fexofenadine HCl
Catalog No. A11859 COX 抑制剂/histamine H1 receptor 激动剂Fexofenadine Hydrochloride是一种抗组胺药，可抑制Cox-1，Cox-2，并且是组胺H1受体激动剂，IC50为246 nM。 了解更多 -
Etoricoxib
Catalog No. A13770 COX-2 抑制剂Etoricoxib特异性结合并抑制环氧合酶2（COX-2），从而抑制花生四烯酸向前列腺素的转化。抑制COX-2可以诱导细胞凋亡并抑制肿瘤细胞的增殖和血管生成。 了解更多 -
Xanthohumol
Catalog No. A15919 -
Meclofenamate Sodium
Catalog No. A12520
23 个项目
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