Epigenetics
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Belinostat (PXD101)
Catalog No. A10122 HDAC 抑制剂Belinostat(PXD101)是一种HDAC抑制剂,可抑制HeLa细胞提取物中的HDAC活性,IC50为27 nM。 了解更多 -
SB939 ( Pracinostat )
Catalog No. A10830 HDAC 抑制剂SB939 (Pracinostat)是HDAC的口服抑制剂,对I,II和IV类HDAC具有选择性,在体外HDAC1活性测定中显示IC50值为77 nM。 了解更多 -
AR-42 (HDAC-42)
Catalog No. A11037 HDAC 抑制剂AR-42 (HDAC-42)是一种新型的HDAC抑制剂,通过下调本构激活的Kit表现出对恶性肥大细胞系的生物学活性。 了解更多 -
CUDC-101
Catalog No. A10246 -
JNJ-26481585 (Quisinostat)
Catalog No. A10492 HDAC 抑制剂JNJ-26481585 (Quisinostat)是一种pan-HDAC抑制剂,对HDAC1具有显著的效力(IC(50),0.16 nmol/L)。 了解更多 -
PCI-24781 (Abexinostat)
Catalog No. A10700 -
Vorinostat (SAHA)
Catalog No. A10979 HDAC 抑制剂Vorinostat (SAHA)是HDAC的抑制剂,抑制脱乙酰和导致双方超乙酰化组蛋白和转录因子的积累。 了解更多 -
LAQ824 (NVP-LAQ824, Dacinostat)
Catalog No. A10516 HDAC 抑制剂LAQ824 (NVP-LAQ824)是一种有效的新型组蛋白去乙酰化酶抑制剂,具有显著的抗多发性骨髓瘤活性。 了解更多 -
Splitomicin
Catalog No. A14221 NAD(+)-dependent histone deacetylase Sir2p 抑制剂Splitomicin是一种选择性的NAD(+)-依赖性组蛋白脱乙酰基酶Sir2p抑制剂,IC50为60 uM,在基于细胞的测定中显示出更高的活性。 了解更多 -
Ac-Lys-AMC
Catalog No. A18461 fluorescent substrate for HDACAc-Lys-AMC (Hexanamide), also termed MAL, is a fluorescent substrate for histone deacetylase HDACs. 了解更多 -
Valproic acid
Catalog No. A17323 HDAC inhibitorValproic acid is an HDAC inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2; Valproic acid sodium salt is used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches. 了解更多 -
ITSA-1
Catalog No. A16127