HMG-CoA Reductase
Catalog No. | Inhibitor Name | HMG-CoA Reductase |
---|---|---|
A10810 | Rosuvastatin Calcium | ** |
A11877 | Lovastatin | *** |
A11912 | Pravastatin sodium | ** |
A11184 | Clinofibrate | * |
A11800 | Atorvastatin Calcium | |
A13709 | Mevastatin |
Notes:
1.Hover mouse over " " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.
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Lovastatin (Mevacor)
Catalog No. A11877 HMG-CoA reductase 抑制剂Lovastatin (Mevacor)是HMG-CoA还原酶的抑制剂,IC50为3.4 nM,用于降低胆固醇。 了解更多 -
Atorvastatin calcium
Catalog No. A11800 HMG-CoA reductase 抑制剂Atorvastatin calcium (Lipitor)是HMG-CoA还原酶的抑制剂,可用作降低胆固醇的药物,可阻止胆固醇的产生。 了解更多 -
Atorvastatin
Catalog No. A13743 HMG-CoA reductase 抑制剂Atorvastatin是一种HMG-CoA还原酶抑制剂(IC50 = 154 nM),可有效治疗高胆固醇血症和某些血脂异常。 了解更多 -
Rosuvastatin calcium (Crestor)
Catalog No. A10810 HMG-CoA reductase 抑制剂Rosuvastatin calcium (Crestor)是他汀类药物中的一员,用于治疗高胆固醇及相关疾病,并预防心血管疾病。罗苏伐他汀是一种竞争性HMG-CoA reductase抑制剂,无细胞试验中IC50为11 nM。 了解更多 -
Swertiamarin
Catalog No. A12128 -
Pitavastatin calcium (Livalo)
Catalog No. A10737 HMG-CoA reductase 抑制剂Pitavastatin calcium (Livalo)是HMGCR(HMG-CoA还原酶)酶的竞争性抑制剂,可降低LDL胆固醇的合成。 了解更多 -
Pitavastatin Lactone
Catalog No. A13896 -
Pravastatin sodium
Catalog No. A11912 HMG-CoA reductase 抑制剂Pravastatin sodium是3-羟基-3-甲基辅酶A(HMG-CoA)还原酶的水溶性竞争性抑制剂。有效阻断体内胆固醇合成(Ki?1 nM)并显示出心脏保护特性。 了解更多 -
Mevastatin
Catalog No. A13709