COX
Catalog No. | Inhibitor Name | COX | COX-1 | COX-2 | Other |
---|---|---|---|---|---|
A10193 | Celecoxib | **** | |||
A10461 | Ibuprofen | * | * | ||
A10474 | Indomethacin | ** | * | ||
A11918 | Rofecoxib | **** | |||
A10304 | Diclofenac Sodium | *** | *** | ||
A11695 | Lornoxicam | **** | **** | ||
A10623 | Naproxen Sodium | * | * | ||
A13342 | Valdecoxib | **** | |||
A11693 | Tolfenamic Acid | *** | |||
A16399 | Amfenac Sodium Monohydrate | ** | *** | ||
A11694 | Nimesulide | * | |||
A12520 | Meclofenamate Sodium | **** | *** | ||
A16428 | Carprofen | **** | |||
A10636 | Nepafenac | ||||
A10878 | Sulindac | ||||
A10565 | Meloxicam | ||||
A10820 | Aspirin | ||||
A11906 | Phenacetin | ||||
A10736 | Piroxicam | ||||
A10462 | Ibuprofen Lysine | ||||
A11641 | Pranoprofen | ||||
A10090 | Asaraldehyde | ||||
A11692 | Acemetacin | ||||
A13244 | Bromfenac Sodium |
Notes:
1.Hover mouse over " " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.
-
Sulindac (Clinoril)
Catalog No. A10878 -
Tepoxalin
Catalog No. A12879 -
Licofelone
Catalog No. A11697 COX/LOX 抑制剂Licofelone是一种COX/LOX双重抑制剂,被认为是治疗骨关节炎的药物。它可能会降低与其他仅抑制COX(环氧合酶)的非甾体类抗炎药有关的胃肠道毒性。利福非酮是第一种同时抑制两者的药物。 了解更多 -
Flunixin meglumine
Catalog No. A11686 COX 抑制剂Flunixin Meglumin是一种有效的环氧化酶(COX)抑制剂,用作止痛剂,具有抗炎和解热作用。 了解更多 -
Acetaminophen
Catalog No. A10030 COX 抑制剂Acetaminophen (paracetamol) 是选择性环氧合酶-2 (COX-2) 的抑制剂,IC50 值为 25.8 μM。Acetaminophen 是一种有效的肝 N-乙酰转移酶 2 (NAT2) 抑制剂。它是广泛使用的解热和止痛药。 了解更多 -
Pravadoline (WIN 48098)
Catalog No. A10749 COX 抑制剂Pravadoline (WIN 48098)是抗炎和前列腺素合成抑制剂,通过抑制环氧合酶(COX)发挥作用。 了解更多 -
Phenylbutazone (Butazolidin, Butatron)
Catalog No. A10720 COX 抑制剂Phenylbutazone (Butazolidin,Butatron)是一种具有研究意义的化合物,它是一种抗炎和抗增殖剂。 了解更多 -
Acemetacin (Emflex)
Catalog No. A11692 -
Naproxen sodium
Catalog No. A10623 COX 抑制剂Naproxen sodium是一种非选择性的环氧合酶(COX)抑制剂,具有抗炎,解热和镇痛作用。对秋水仙碱引起的认知障碍和氧化应激具有神经保护作用。 了解更多 -
Amfenac Sodium Monohydrate
Catalog No. A16399 COX 抑制剂Amfenac Sodium Monohydrate是一种非甾体止痛消炎药,带有乙酸部分。COX1和COX2的IC50值分别为250 nM和150 nM。 了解更多