COX
Catalog No. | Inhibitor Name | COX | COX-1 | COX-2 | Other |
---|---|---|---|---|---|
A10193 | Celecoxib | **** | |||
A10461 | Ibuprofen | * | * | ||
A10474 | Indomethacin | ** | * | ||
A11918 | Rofecoxib | **** | |||
A10304 | Diclofenac Sodium | *** | *** | ||
A11695 | Lornoxicam | **** | **** | ||
A10623 | Naproxen Sodium | * | * | ||
A13342 | Valdecoxib | **** | |||
A11693 | Tolfenamic Acid | *** | |||
A16399 | Amfenac Sodium Monohydrate | ** | *** | ||
A11694 | Nimesulide | * | |||
A12520 | Meclofenamate Sodium | **** | *** | ||
A16428 | Carprofen | **** | |||
A10636 | Nepafenac | ||||
A10878 | Sulindac | ||||
A10565 | Meloxicam | ||||
A10820 | Aspirin | ||||
A11906 | Phenacetin | ||||
A10736 | Piroxicam | ||||
A10462 | Ibuprofen Lysine | ||||
A11641 | Pranoprofen | ||||
A10090 | Asaraldehyde | ||||
A11692 | Acemetacin | ||||
A13244 | Bromfenac Sodium |
Notes:
1.Hover mouse over " " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.
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Diclofenac sodium
Catalog No. A10304 COX 抑制剂Diclofenac Sodium是一种非选择性的COX抑制剂,完整细胞中的COX-1和-2的IC50分别为0.5μg/ml和0.5μg/ml,作用于绵羊COX-1和COX-2, IC50分别为60和220 nM,用作非甾体类抗炎药(NSAID)来减轻疼痛和减轻疼痛 肿胀发炎。 了解更多 -
(-)-Epicatechin
Catalog No. A12043 COX-1 抑制剂(-)-Epicatechin是绿茶的天然产物。(-)表儿茶素是cox-1的抑制剂。 了解更多 -
Ibuprofen Lysine (NeoProfen)
Catalog No. A10462 -
Fexofenadine HCl
Catalog No. A11859 COX 抑制剂/histamine H1 receptor 激动剂Fexofenadine Hydrochloride是一种抗组胺药,可抑制Cox-1,Cox-2,并且是组胺H1受体激动剂,IC50为246 nM。 了解更多 -
Xanthohumol
Catalog No. A15919 -
Indomethacin (Indocid, Indocin)
Catalog No. A10474 COX 抑制剂Indomethacin (Indocid, Indocin)是一种非选择性COX1和COX2抑制剂,IC50分别为0.1 μg/mL和5 μg/mL。吲哚美辛(吲哚满,吲哚满)是一种非甾体抗炎药,通常用于减轻发热、疼痛、僵硬和肿胀。 了解更多 -
Meclofenamate Sodium
Catalog No. A12520 -
Lornoxicam (Xefo)
Catalog No. A11695 COX 抑制剂Lornoxicam (Xefo)是一种非甾体类COX-1/COX-2抑制剂。它是oxicam类的非甾体类抗炎药(NSAID),具有镇痛(缓解疼痛),抗炎和退烧(退烧)特性。 了解更多 -
(S)-(+)-Flurbiprofen
Catalog No. A12434 COX 抑制剂(S)-(+)-Flurbiprofen是一种非选择性的Cox-1和Cox-2抑制剂。 了解更多 -
SC 560
Catalog No. A13023 -
Ibuprofen (Advil)
Catalog No. A10461 COX-1 抑制剂Ibuprofen (Advil)是一种非甾体抗炎药(NSAID),靶向COX-1,IC50为13 μM。 了解更多 -
Piroxicam (Feldene)
Catalog No. A10736