Reverse Transcriptase

Catalog No.Inhibitor Name Reverse TranscriptaseOther
A10306Didanosine
**
A12587Dapivirine (TMC120)
***
A10908Tenofovir
A10909Tenofovir Disoproxil Fumarate
A10349Emtricitabine
A11216Entecavir Hydrate
A10039Adefovir Dipivoxil
A10639Nevirapine
A10512Lamivudine
A15428Zidovudine
A11120Abacavir sulfate
A11542Rilpivirine

Notes:
1.Hover mouse over " * " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " * " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.

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  1. Loviride

    Catalog No. A21996
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    non-nucleoside reverse transcriptase inhibitor
    Loviride (R 89439) is a non-nucleoside reverse transcriptase inhibitor (NNRTI), with an IC50 of 0.3 ?M for reverse transcriptase from HIV-1. Loviride (R 89439) inhibits HIV-1, HIV-2 and SIV replication in MT-4 cells. 了解更多
  2. Tenofovir maleate

    Catalog No. A21776
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    nucleotide reverse transcriptase inhibitor
    Tenofovir Disoproxil Fumarate is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B. 了解更多
  3. Delavirdine

    Catalog No. A21469
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    non-nucleoside reverse transcriptase inhibitor
    Delavirdine(U 90152) is a potent non-nucleoside reverse transcriptase inhibitor (NNRTI). 了解更多
  4. Tenofovir alafenamide hemifumarate

    Catalog No. A18050
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    HIV-1 nucleotide reverse transcriptase inhibitor
    Tenofovir alafenamide hemifumarate (GS-7340 hemifumarate) is an investigational oral prodrug of Tenofovir. Tenofovir is a HIV-1 nucleotide reverse transcriptase inhibitor. 了解更多
  5. Tenofovir alafenamide fumarate

    Catalog No. A18049
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    HIV-1 nucleotide reverse transcriptase inhibitor
    Tenofovir alafenamide fumarate (GS-7340 fumarate) is an investigational oral prodrug of Tenofovir. Tenofovir is a HIV-1 nucleotide reverse transcriptase inhibitor. 了解更多
  6. Tenofovir hydrate

    Catalog No. A18042
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    nucleotide reverse transcriptase inhibitor
    Tenofovir hydrate is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B. 了解更多
  7. Tenofovir Disoproxil

    Catalog No. A18041
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    nucleotide reverse transcriptase inhibitor
    Tenofovir Disoproxil (Bis(POC)-PMPA) is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B. 了解更多
  8. Zalcitabine

    Catalog No. A11005
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    nucleoside analogue reverse transcriptase inhibitor
    Zalcitabine is a potent nucleoside analogue reverse transcriptase inhibitor used in the treatment of HIV infection. 了解更多
  9. MIV-150

    Catalog No. A12060
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    NNRT inhibitor
    MIV-150 is a nonnucleoside reverse transcriptase (NNRT) inhibitor, blocking HIV-1 and HIV-2 infections, with an EC50<1 nM against HIV-1/HIV-2MN. 了解更多
  10. Etravirine ( R165335, TMC125)

    Catalog No. A11417
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    NNRT inhibitor
    Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV. 了解更多
  11. 4'-Ethynyl-2'-deoxyadenosine

    Catalog No. A18513
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    nucleoside reverse transcriptase (RT) inhibitor
    4'-Ethynyl-2'-deoxyadenosine (4'-E-dA), a nucleoside reverse transcriptase (RT) inhibitor, is an antiretroviral agent which is potent against drug-resistant HIV variants, with an EC50 of 98 nM in MT-4 cells for anti-HIV-1 activity. 了解更多
  12. Delavirdine mesylate

    Catalog No. A13274
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    NNRT 抑制剂
    Delavirdine是一种有效的人类免疫缺陷病毒1型(HIV-1)逆转录酶(RT)抑制剂。 了解更多
  13. (Z)-9-Propenyladenine

    Catalog No. A21687
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    (Z)-9-Propenyladenine is a mutagenic impurity in tenofovir disoproxil fumarate. Tenofovir is an antiretroviral drug known as nucleotide analogue reverse transcriptase (NtART) inhibitor, which blocks reverse transcriptase, a crucial virus enzyme in HIV-1 and HBV. 了解更多
  14. GS-7340

    Catalog No. A15772
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    NRT 抑制剂
    GS-7340是替诺福韦(TFV)的前药,它比TFV富马酸二甲酚更有效地将TFV输送到淋巴样细胞和组织中。 了解更多
  15. Zidovudine

    Catalog No. A15428
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    NRTI 抑制剂
    Zidovudine是一种核苷类似物逆转录酶抑制剂(NRTI),是一种用于治疗HIV/AIDS感染的抗逆转录病毒药物。叠氮胸苷降低了CRISPR介导的同源性定向修复(HDR)的效率。 了解更多
  16. Elvucitabine

    Catalog No. A14435
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    NRT 抑制剂
    Elvucitabine是一种实验性的核苷逆转录酶抑制剂(NRTI)。 了解更多
  17. Lamivudine

    Catalog No. A10512
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    Lamivudine是一种有效的核苷类似物逆转录酶抑制剂(nRTI)。 了解更多
  18. Lersivirine (UK-453061)

    Catalog No. A12667
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    NNRT 抑制剂
    Lersivirine (UK-453061)是新一代的非核苷类逆转录酶抑制剂(NNRTI),IC50为119 nM,对野生型HIV-1和一些非核苷类逆转录酶抑制剂耐药菌株具有活性。 了解更多
  19. Dapivirine

    Catalog No. A12587
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    HIV reverse transcriptase 抑制剂
    Dapivirine是一种有效的非核苷逆转录酶抑制剂(NNRTI)。 了解更多
  20. Nevirapine (Viramune)

    Catalog No. A10639
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    Nevirapine (Viramune)是有效的(IC50 = 84nM)HIV-1逆转录酶的选择性非核苷抑制剂。 了解更多
  21. Doravirine (MK-1439)

    Catalog No. A12443
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    NNRT 抑制剂
    MK-1439是非核苷逆转录酶抑制剂。 了解更多
  22. Didanosine

    Catalog No. A10306
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    Reverse transcriptase 抑制剂
    Didanosine是一种逆转录酶抑制剂,对HIV有效,可与其他抗逆转录病毒药物疗法联合使用。 了解更多
  23. Emtricitabine

    Catalog No. A10349
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    NRT 抑制剂
    Emtricitabine是一种用于治疗HIV感染的核苷逆转录酶抑制剂 (NRTI) 。 了解更多
  24. Rilpivirine (R 278474, TMC 278)

    Catalog No. A11542
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    NNRT 抑制剂
    Rilpivirine (R 278474,TMC 278)是第二代非核苷逆转录酶抑制剂(NNRTI),与较老的NNRTIs(例如依非韦伦)相比,具有更高的效力,更长的半衰期和更低的副作用。 了解更多
  25. Adefovir dipivoxil

    Catalog No. A10039
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    ntRT inhibitor
    Adefovir dipivoxil是口服的核苷酸类似物逆转录酶抑制剂(ntRTI)。 了解更多
  26. Abacavir

    Catalog No. A11115
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    Transcriptase 抑制剂
    Abacavir是一种核苷类似物逆转录酶抑制剂(NRTI);鸟苷类似物用于治疗艾滋病毒和艾滋病。 了解更多
  27. Abacavir sulfate

    Catalog No. A11120
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    Transcriptase 抑制剂
    Abacavir sulfate是一种核苷类似物逆转录酶抑制剂(NRTI)。 了解更多
  28. Tenofovir Disoproxil Fumarate

    Catalog No. A10909
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    nucleotide reverse transcriptase 抑制剂
    Tenofovir Disoproxil Fumarate属于一类抗逆转录病毒药物,其通过与天然底物脱氧腺苷5’-三磷酸盐竞争以及整合到DNA后终止DNA链抑制HIV reverse transcriptase活性。 了解更多
  29. Entecavir hydrate

    Catalog No. A11216
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    Reverse transcriptase 抑制剂
    Entecavir hydrate,一个新的脱氧鸟嘌呤核苷类似物,是乙肝病毒复制的选择性抑制剂。 了解更多
  30. Tenofovir (Viread)

    Catalog No. A10908
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    HIV reverse transcriptase 抑制剂
    Tenofovir (Viread)属于一类称为核苷逆转录酶抑制剂(NRTIs)的药物。它通过减少血液中的HIV含量起作用。 了解更多

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