Reverse Transcriptase
Catalog No. | Inhibitor Name | Reverse Transcriptase | Other |
---|---|---|---|
A10306 | Didanosine | ** | |
A12587 | Dapivirine (TMC120) | *** | |
A10908 | Tenofovir | ||
A10909 | Tenofovir Disoproxil Fumarate | ||
A10349 | Emtricitabine | ||
A11216 | Entecavir Hydrate | ||
A10039 | Adefovir Dipivoxil | ||
A10639 | Nevirapine | ||
A10512 | Lamivudine | ||
A15428 | Zidovudine | ||
A11120 | Abacavir sulfate | ||
A11542 | Rilpivirine |
Notes:
1.Hover mouse over " " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.
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(Z)-9-Propenyladenine
Catalog No. A21687 (Z)-9-Propenyladenine is a mutagenic impurity in tenofovir disoproxil fumarate. Tenofovir is an antiretroviral drug known as nucleotide analogue reverse transcriptase (NtART) inhibitor, which blocks reverse transcriptase, a crucial virus enzyme in HIV-1 and HBV. 了解更多 -
GS-7340
Catalog No. A15772 -
Zidovudine
Catalog No. A15428 NRTI 抑制剂Zidovudine是一种核苷类似物逆转录酶抑制剂(NRTI),是一种用于治疗HIV/AIDS感染的抗逆转录病毒药物。叠氮胸苷降低了CRISPR介导的同源性定向修复(HDR)的效率。 了解更多 -
Lamivudine
Catalog No. A10512 Lamivudine是一种有效的核苷类似物逆转录酶抑制剂(nRTI)。 了解更多 -
Lersivirine (UK-453061)
Catalog No. A12667 NNRT 抑制剂Lersivirine (UK-453061)是新一代的非核苷类逆转录酶抑制剂(NNRTI),IC50为119 nM,对野生型HIV-1和一些非核苷类逆转录酶抑制剂耐药菌株具有活性。 了解更多 -
Dapivirine
Catalog No. A12587 -
Nevirapine (Viramune)
Catalog No. A10639 Nevirapine (Viramune)是有效的(IC50 = 84nM)HIV-1逆转录酶的选择性非核苷抑制剂。 了解更多 -
Didanosine
Catalog No. A10306 -
Emtricitabine
Catalog No. A10349 -
Rilpivirine (R 278474, TMC 278)
Catalog No. A11542 NNRT 抑制剂Rilpivirine (R 278474,TMC 278)是第二代非核苷逆转录酶抑制剂(NNRTI),与较老的NNRTIs(例如依非韦伦)相比,具有更高的效力,更长的半衰期和更低的副作用。 了解更多 -
Adefovir dipivoxil
Catalog No. A10039 ntRT inhibitorAdefovir dipivoxil是口服的核苷酸类似物逆转录酶抑制剂(ntRTI)。 了解更多 -
Abacavir
Catalog No. A11115 -
Abacavir sulfate
Catalog No. A11120 -
Tenofovir Disoproxil Fumarate
Catalog No. A10909 nucleotide reverse transcriptase 抑制剂Tenofovir Disoproxil Fumarate属于一类抗逆转录病毒药物,其通过与天然底物脱氧腺苷5’-三磷酸盐竞争以及整合到DNA后终止DNA链抑制HIV reverse transcriptase活性。 了解更多 -
Entecavir hydrate
Catalog No. A11216 Reverse transcriptase 抑制剂Entecavir hydrate,一个新的脱氧鸟嘌呤核苷类似物,是乙肝病毒复制的选择性抑制剂。 了解更多 -
Tenofovir (Viread)
Catalog No. A10908 HIV reverse transcriptase 抑制剂Tenofovir (Viread)属于一类称为核苷逆转录酶抑制剂(NRTIs)的药物。它通过减少血液中的HIV含量起作用。 了解更多 -
Tenofovir maleate
Catalog No. A21776 nucleotide reverse transcriptase inhibitorTenofovir Disoproxil Fumarate is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B. 了解更多 -
Delavirdine
Catalog No. A21469 non-nucleoside reverse transcriptase inhibitorDelavirdine(U 90152) is a potent non-nucleoside reverse transcriptase inhibitor (NNRTI). 了解更多 -
Tenofovir alafenamide hemifumarate
Catalog No. A18050 HIV-1 nucleotide reverse transcriptase inhibitorTenofovir alafenamide hemifumarate (GS-7340 hemifumarate) is an investigational oral prodrug of Tenofovir. Tenofovir is a HIV-1 nucleotide reverse transcriptase inhibitor. 了解更多 -
Tenofovir alafenamide fumarate
Catalog No. A18049 HIV-1 nucleotide reverse transcriptase inhibitorTenofovir alafenamide fumarate (GS-7340 fumarate) is an investigational oral prodrug of Tenofovir. Tenofovir is a HIV-1 nucleotide reverse transcriptase inhibitor. 了解更多 -
Tenofovir hydrate
Catalog No. A18042 nucleotide reverse transcriptase inhibitorTenofovir hydrate is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B. 了解更多 -
Tenofovir Disoproxil
Catalog No. A18041 nucleotide reverse transcriptase inhibitorTenofovir Disoproxil (Bis(POC)-PMPA) is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B. 了解更多 -
Zalcitabine
Catalog No. A11005 nucleoside analogue reverse transcriptase inhibitorZalcitabine is a potent nucleoside analogue reverse transcriptase inhibitor used in the treatment of HIV infection. 了解更多 -
Etravirine ( R165335, TMC125)
Catalog No. A11417 NNRT inhibitorEtravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV. 了解更多 -
4'-Ethynyl-2'-deoxyadenosine
Catalog No. A18513 nucleoside reverse transcriptase (RT) inhibitor4'-Ethynyl-2'-deoxyadenosine (4'-E-dA), a nucleoside reverse transcriptase (RT) inhibitor, is an antiretroviral agent which is potent against drug-resistant HIV variants, with an EC50 of 98 nM in MT-4 cells for anti-HIV-1 activity. 了解更多 -
Delavirdine mesylate
Catalog No. A13274