Bcl-2 Family
Catalog No. | Inhibitor Name | Bcl-2 | Bcl-B | Bcl-w | Bcl-xL | Mcl-1 | A1 | Bax | Other |
---|---|---|---|---|---|---|---|---|---|
A10255 | ABT-737 | **** | * | *** | *** | ||||
A10022 | Navitoclax (ABT-263) | **** | **** | **** | ** | ** | |||
A10665 | Obatoclax Mesylate | *** | |||||||
A10955 | TW-37 | *** | * | *** | |||||
A12500 | Venetoclax | **** | *** | **** | |||||
A15004 | AT101 | ** | ** | *** | |||||
A11448 | HA14-1 | * | |||||||
A12823 | Sabutoclax | ** | ** | *** | ** | ||||
A15545 | A-1210477 | **** | |||||||
A14222 | UMI-77 | ** | |||||||
A11988 | Gambogic Acid | * | * | **** | * | * | * | Caspase | |
A12743 | BM-1074 | **** | **** | ||||||
A13327 | WEHI-539 hydrochloride | **** | |||||||
A15821 | BDA-366 | *** | |||||||
A16061 | BH3I-1 | * | p53 | ||||||
A16112 | A-1155463 | **** | |||||||
A16190 | A-1331852 | **** | |||||||
A16314 | Apogossypolone (ApoG2) |
Notes:
1.Hover mouse over " " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.
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Bax channel blocker
Catalog No. A15335 -
Bax inhibitor peptide, negative control
Catalog No. A15338 -
Bax inhibitor peptide P5
Catalog No. A15336 Bax 抑制剂Bax inhibitor peptide P5,Bax易位至线粒体的细胞渗透性合成肽抑制剂;由Ku70设计的一种蛋白质,被认为可抑制Bax的线粒体易位。在体外抑制Bax介导的细胞凋亡。 了解更多 -
Bax inhibitor peptide V5
Catalog No. A15337 Bax 抑制剂Bax inhibitor peptide V5,Bax易位至线粒体的细胞渗透性合成肽抑制剂;由Ku70设计的一种蛋白质,被认为可抑制Bax的线粒体易位。在体外抑制Bax介导的细胞凋亡。 了解更多