PARP

Catalog No.Inhibitor Name PARPPARP1PARP2PARP3V-PARPTankyrase-1
A10111Olaparib
***
****
*
A10026Veliparib
***
***
A14182Rucaparib
****
A11243Talazoparib
****
A10046AG-14361
***
A10475INO-1001
**
A10019A-966492
****
****
A15215PJ34
***
A12665PJ34 HCl
***
A11026Niraparib
***
****
*
**
**
A12750UPF 1069
*
**
A14309ME0328
*
**
A14371Benzamide
*
A15375NU1025
**
A10164Iniparib
A12393AZD2461
A16344BGP-15
A10045AG-014699 (Rucaparib)
****
A153704-HQN
*
A15371BYK 204165
*
*
A15372BYK 49187
*
*
A15374EB 47
**
A15373DR 2313
*
**

Notes:
1.Hover mouse over " * " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " * " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.

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  1. MK-4827 (Niraparib)

    Catalog No. A11026
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    PARP 抑制剂
    MK-4827 (Niraparib)是一种新型有效的口服生物可利用的PARP-1和PARP-2抑制剂。 了解更多
  2. UPF 1069

    Catalog No. A12750
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    PARP2 抑制剂
    UPF 1069是一种选择性聚(ADP-核糖)聚合酶(PARP)2抑制剂(PARP-2和PARP-1的IC50值分别为0.3和8.0μM)。 了解更多
  3. DR 2313

    Catalog No. A15373
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    PARP 抑制剂
    DR 2313是一种水溶性嘧啶酮化合物,起PARP(聚(ADP-核糖)聚合酶)抑制剂的作用。 了解更多
  4. BYK 49187

    Catalog No. A15372
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    PARP-1/PARP-2 抑制剂
    BYK 49187,PARP-1和PARP-2抑制剂(无细胞重组PARP-1和鼠PARP-2的pIC50值分别为8.36和7.50)。 了解更多

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