renin-angiotensin-aldosterone system (RAAS)
Catalog No. | Inhibitor Name | AT1 receptor | AT2 receptor | ACE | Renin | RAAS |
---|---|---|---|---|---|---|
A11123 | Aliskiren Hemifumarate | *** | ||||
A10175 | Candesartan | **** | ||||
A10351 | Enalaprilat Dihydrate | *** | *** | **** | ||
A10477 | Irbesartan | *** | ||||
A13201 | PD123319 | * | ||||
A10710 | Perindopril Erbumine | *** | ||||
A10176 | Candesartan Cilexetil | **** | ||||
A10778 | Ramipril | ** | ||||
A11738 | Captopril | * | ||||
A16420 | Azilsartan Medoxomil | ** | ||||
A13747 | Eprosartan Mesylate | **** | ||||
A11775 | Azilsartan | ** | ||||
A10905 | Telmisartan | |||||
A10123 | Benazepril HCl | |||||
A10350 | Enalapril Maleate | |||||
A11615 | Olmesartan Medoxomil | |||||
A11747 | Cilazapril Monohydrate | |||||
A11876 | Lisinopril | |||||
A11745 | Moexipril HCl | |||||
A11749 | Temocapril | |||||
A11736 | Quinapril HCl | |||||
A14206 | LCZ696 | |||||
A11748 | Fosinopril Sodium |
Notes:
1.Hover mouse over " " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.
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Eprosartan
Catalog No. A11121 -
Olmesartan (RNH6270, CS-088)
Catalog No. A10670 Olmesartan (RNH6270,CS-088)是一种用于治疗高血压的血管紧张素II受体拮抗剂。 了解更多 -
Olmesartan medoxomil
Catalog No. A11615 Olmesartan medoxomil是一种用于治疗高血压的血管紧张素II受体拮抗剂。奥美沙坦通过阻断血管紧张素II与血管肌肉AT1受体的结合来发挥作用。通过阻断结合而不是血管紧张素II的合成,奥美沙坦抑制了对肾素分泌的负面调节反馈。 了解更多 -
Zofenopril calcium
Catalog No. A12769 -
Azilsartan (TAK-536)
Catalog No. A11775 -
Telmisartan
Catalog No. A10905 -
Tasosartan
Catalog No. A10891 -
Eprosartan mesylate
Catalog No. A13747 Eprosartan mesylate是一种竞争性的AT1受体拮抗剂,IC50值为1.4-3.9 nM,消除半衰期为5至7小时。 了解更多