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￥ 0.00 renin-angiotensin-aldosterone system (RAAS)
| Catalog No. | Inhibitor Name | AT1 receptor | AT2 receptor | ACE | Renin | RAAS |
|---|---|---|---|---|---|---|
| A11123 | Aliskiren Hemifumarate | *** | ||||
| A10175 | Candesartan | **** | ||||
| A10351 | Enalaprilat Dihydrate | *** | *** | **** | ||
| A10477 | Irbesartan | *** | ||||
| A13201 | PD123319 | * | ||||
| A10710 | Perindopril Erbumine | *** | ||||
| A10176 | Candesartan Cilexetil | **** | ||||
| A10778 | Ramipril | ** | ||||
| A11738 | Captopril | * | ||||
| A16420 | Azilsartan Medoxomil | ** | ||||
| A13747 | Eprosartan Mesylate | **** | ||||
| A11775 | Azilsartan | ** | ||||
| A10905 | Telmisartan | |||||
| A10123 | Benazepril HCl | |||||
| A10350 | Enalapril Maleate | |||||
| A11615 | Olmesartan Medoxomil | |||||
| A11747 | Cilazapril Monohydrate | |||||
| A11876 | Lisinopril | |||||
| A11745 | Moexipril HCl | |||||
| A11749 | Temocapril | |||||
| A11736 | Quinapril HCl | |||||
| A14206 | LCZ696 | |||||
| A11748 | Fosinopril Sodium |
Notes:
1.Hover mouse over "" to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of "" is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.
17 个项目
每页
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Azilsartan Medoxomil
Catalog No. A16420 angiotensin II receptor type 1 拮抗剂Azilsartan medoxomil是一种口服给药的1型血管紧张素II受体拮抗剂，IC50为0.62 nM。 了解更多 -
Tasosartan
Catalog No. A10891 -
Telmisartan
Catalog No. A10905 -
Fimasartan
Catalog No. A17477 non-peptide angiotensin II receptor antagonistFimasartan is a non-peptide angiotensin II receptor antagonist (ARB) used for the treatment of hypertension and heart failure. Through oral administration, fimasartan blocks angiotensin II receptor type 1 (AT1 receptors), reducing pro-hypertensive actions of angiotensin II, such as systemic vasoconstriction and water retention by the kidneys. 了解更多 -
Azilsartan D5
Catalog No. A21600 angiotensin II type 1 receptor antagonistAzilsartan D5 is the deuterium labeled Azilsartan(TAK-536), which is a specific and potent angiotensin II type 1 receptor antagonist. 了解更多 -
Losartan (D4 Carboxylic Acid)
Catalog No. A21578 angiotensin II receptor antagonistLosartan D4 Carboxylic Acid is the deuterium labeled Losartan(EXP-3174), which is an angiotensin II receptor antagonist. 了解更多 -
Eprosartan
Catalog No. A11121 -
Sparsentan
Catalog No. A20879 angiotensin II and endothelin A receptor antagonistSparsentan (RE-021) is a highly potent dual angiotensin II and endothelin A receptor antagonist with Kis of 0.8 and 9.3 nM, respectively. 了解更多 -
Azilsartan medoxomil monopotassium
Catalog No. A20860 angiotensin II receptor type 1 antagonistAzilsartan medoxomil monopotassium is an orally administered angiotensin II receptor type 1 antagonist with IC50 of 0.62 nM, which used in the treatment of adults with essential hypertension. 了解更多 -
EXP-3174
Catalog No. A15451 -
Candesartan (Atacand)
Catalog No. A10175 RAAS 拮抗剂Candesartan (Atacand)是一种血管紧张素受体阻滞剂（也称为血管紧张素II受体拮抗剂或AIIRA）。 了解更多 -
Irbesartan (Avapro)
Catalog No. A10477 -
PD 123319 ditrifluoroacetate
Catalog No. A13201 angiotensin AT2 receptor 拮抗剂PD 123319 ditrifluoroacetate是一种有效的，选择性的非肽血管紧张素AT2受体拮抗剂。大鼠肾上腺组织和大脑的IC50值分别为34和210 nM。 了解更多
17 个项目
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