FAK

Inhibitory Selectivity

Catalog No.	Inhibitor Name	FAK	Other
A12580	PF-00562271	****	CDK2/CyclinE,CDK3/CyclinE,CDK1/CyclinB
A11192	PF-562271	****	CDK2/CyclinE,CDK3/CyclinE,CDK1/CyclinB
A11235	PF-573228	*
A11507	TAE226	**	Insulin Receptor,IGF-1R,c-Met
A11171	PF-03814735	*	Aurora A,Aurora B,FLT1
A11142	PF-431396	**
A13140	PND-1186	****
A11929	Defactinib
A15543	CEP-37440	**	ALK
A15765	GSK2256098	****

Notes:
1.Hover mouse over " * " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " * " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.

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PF-03814735

Catalog No. A11171
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Aurora A/B Kinase 抑制剂

PF-03814735是一种新颖，有效且可逆的Aurora A/B抑制剂，IC50为0.8 nM/5 nM，对Flt3，FAK，TrkA的效力较低，对Met和FGFR1的活性最低。了解更多

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