VEGFR

Inhibitory Selectivity

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Catalog No.	Inhibitor Name	VEGFR1	VEGFR2	VEGFR3	Other
A10001	Sorafenib Tosylate		**		Raf-1,B-Raf,B-Raf (V599E)
A10025	Linifanib	****	****	*	CSF-1R,FLT3,Kit
A10043	AEE788	*	*	*	EGFR,HER2/ErbB2,c-Abl
A10080	Ponatinib		****		Abl,PDGFRα,FGFR1
A10101	Tivozanib	**	***	**	EphB2,PDGFRα,PDGFRβ
A10103	Axitinib	****	****	****	PDGFRβ,Kit,PDGFRα
A10137	Nintedanib	**	***	***	LCK,FLT3,FGFR2
A10154	BMS-794833		**		Met
A10162	Brivanib Alaninate	*	**		FGFR1
A10185	Cediranib	***	****	****	c-Kit,PDGFRβ,FGFR1

Showing 1 to 10 of 54 entries

Notes:
1.Hover mouse over " * " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " * " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.

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E-3810

Catalog No. A15073
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VEGFR/FGFR 抑制剂

E-3810是一种有效且选择性的VEGF和FGF受体双重抑制剂，对VEGFR-1，VEGFR-2，VEGFR-3，FGFR-1和VEGF的IC50值分别为7nM，25nM，10nM，17.5nM和82.5nM。FGFR-2。了解更多

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Nintedanib esylate

Catalog No. A16197
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RTK 抑制剂

Nintedanib esylate是多种受体酪氨酸激酶（RTK）和非受体酪氨酸激酶（nRTK）的有效抑制剂。了解更多

Product Citations (2)

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- Thibaut Fourniols, .et al. Inhibition of Colorectal Cancer-Associated Fibroblasts by Lipid Nanocapsules Loaded With Acriflavine or Paclitaxel, Int J Pharm, 2020, Jun 30;584:119337 PMID: 32371002
- Majid Momeny, .et al. Cediranib, an inhibitor of vascular endothelial growth factor receptor kinases, inhibits proliferation and invasion of prostate adenocarcinoma cells, Eur J Pharmacol, 2020, 882:173298
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LY 2874455

Catalog No. A11244
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FGFR/VEGFR2 抑制剂

LY2874455是一种新型有效的FGFR / VEGFR抑制剂。了解更多

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