Protein Kinase C (PKC)

Catalog No.Inhibitor Name PKCPKCαPKCβPKCγPKCδPKCεPKCζPKCηPKCθPKCμOther
A10356Enzastaurin
**
***
*
*
A11554Sotrastaurin
****
****
****
****
****
****
A10864Staurosporine
****
****
**
*
*
****
c-Fgr,phosphorylase kinase,S6 kinase
A13790Go 6983
***
***
***
***
**
*
A13197Bisindolylmaleimide I
**
***
**
PDGFR
A13514Ro 31-8220 Mesylate
****
***
**
**
A12650Midostaurin
**
**
**
*
*
*
*
PPK,KDR,c-Syk
A12419Go6976
***
****
***
FLT3,JAK2
A10766Quercetin
Sirtuin,Src,PI3Kγ
A10616Myricitrin
A10196Chelerythrine chloride
*
A10261Bryostatin 1
***
A10286Daphnetin
*
EGFR, PKA
A12399Ruboxistaurin (LY333531)
*
****
*
*
**
A14871PKC (19-36)
*

Notes:
1.Hover mouse over " * " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " * " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.

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  1. DCPLA-ME

    Catalog No. A21368
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    PKCε activator
    DCPLA-ME, the methyl ester form of DCPLA, is a potent PKCε activator for use in the treatment of neurodegenerative diseases. 了解更多
  2. Roy-Bz

    Catalog No. A13348
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    PKCδ activator
    Roy-Bz is a selecive PKCδ activator. Roy-Bz potently inhibits the proliferation of colon cancer cells by inducing a PKCδ-dependent mitochondrial apoptotic pathway involving caspase-3 activation. 了解更多
  3. (-)-Indolactam V

    Catalog No. A13043
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    PKC activator
    (-)-Indolactam V是一种蛋白激酶C激活剂,可将人ES细胞衍生的定形内胚层强有力地引导至胰腺内胚层中。 了解更多
  4. 12-O-tetradecanoyl phorbol-13-acetate

    Catalog No. A14616
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    PKC activator
    12-O-tetradecanoyl phorbol-13-acetate是佛波醇的二酯,是从巴豆油中提取的促肿瘤化合物。它是在体内和体外以nM浓度可逆的高效蛋白激酶C(PKC)激活剂。 了解更多
  5. Prostratin

    Catalog No. A13679
    PKC activator
    Prostratin是一种蛋白质激酶C激活剂,存在于萨摩亚(Homalanthus nutans)的马拉马拉树的树皮中。 了解更多

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