Epigenetic Reader Domain
Catalog No. | Inhibitor Name | Epigenetic Reader Domain |
---|---|---|
A12729 | (*)-JQ1 | *** |
A11783 | I-BET151 | * |
A12545 | PFI-1 | ** |
A11440 | I-BET-762 | *** |
A13956 | RVX-208 | * |
A13227 | SGC-CBP30 | **** |
A13163 | Bromosporine | **** |
A13890 | OTX015 | **** |
A12948 | UNC1215 | ** |
A13717 | UNC669 | * |
A14133 | GSK1324726A | *** |
A13749 | MS436 | ** |
A13068 | CPI-203 | *** |
A13957 | PFI-3 |
Notes:
1.Hover mouse over " " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.
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BRD7-IN-1 free base
Catalog No. A21530 BRD7-IN-1 free base, a modified derivative of BI7273 (BRD7/9 inhibitor), binds to a VHL ligand via a linker to form a PROTAC VZ185 (VZ185 against BRD7/9 with DC50s of 4.5 and 1.8 nM, respectively). 了解更多 -
BAZ2-ICR
Catalog No. A15947 -
EML 425
Catalog No. A16180 -
UNC 926 hydrochloride
Catalog No. A15367 -
CeMMEC13
Catalog No. A16355 -
CPI-637
Catalog No. A16470 -
ABBV-744
Catalog No. A16831 -
BAY1238097
Catalog No. A16881 BET 抑制剂BAY1238097是一种有效的选择性BET抑制剂。BAY1238097与BET蛋白BRD上的乙酰化赖氨酸识别基序结合,从而防止BET蛋白与组蛋白之间的相互作用。 了解更多 -
HJB-97
Catalog No. A16872 -
ARV-825
Catalog No. A16859 -
dBET1
Catalog No. A16858 -
E-7386
Catalog No. A17089 -
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最新产品
MZ1
Catalog No. A17014 -
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PLX51107
Catalog No. A18345 selective BET inhibitorPLX51107 is a potent and selective BET inhibitor, with Kds of 1.6, 2.1, 1.7, and 5 nM for BD1 and 5.9, 6.2, 6.1, and 120 nM for BD2 of BRD2, BRD3, BRD4, and BRDT, respectively; PLX51107 also interacts with the bromodomains of CBP and EP300 (Kd, in the 100 nM range). 了解更多 -
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最新产品
Mivebresib (ABBV-075)
Catalog No. A17226 BET inhibitorMivebresib, also known as ABBV-075, is a potent BET inhibitor (bromodomain (BRD)-containing proteind) with potential antineoplastic activity. 了解更多 -