Epigenetic Reader Domain
Catalog No. | Inhibitor Name | Epigenetic Reader Domain |
---|---|---|
A12729 | (*)-JQ1 | *** |
A11783 | I-BET151 | * |
A12545 | PFI-1 | ** |
A11440 | I-BET-762 | *** |
A13956 | RVX-208 | * |
A13227 | SGC-CBP30 | **** |
A13163 | Bromosporine | **** |
A13890 | OTX015 | **** |
A12948 | UNC1215 | ** |
A13717 | UNC669 | * |
A14133 | GSK1324726A | *** |
A13749 | MS436 | ** |
A13068 | CPI-203 | *** |
A13957 | PFI-3 |
Notes:
1.Hover mouse over " " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.
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GSK 1210151A (I-BET151)
Catalog No. A11783 BET Bromodomain 抑制剂GSK 1210151A (I-BET151)是溴结构域和额外末端(BET)家族蛋白BRD2,BRD3和BRD4的新型选择性抑制剂。 了解更多 -
Bromosporine
Catalog No. A13163 bromodomain 抑制剂Bromosporine是一种针对溴结构域的广谱抑制剂,对于BRD2,BRD4,BRD9和CECR2的IC50分别为0.41μM,0.29μM,0.122μM和0.017μM。 了解更多 -
OTX015
Catalog No. A13890 -
GSK1324726A (I-BET726)
Catalog No. A14133 BET 抑制剂GSK1324726A (I-BET726)是一种新型、高效、选择性的BET蛋白小分子抑制剂,对BRD2(IC50 = 41 nM)、BRD3(IC50 = 31 nM)和BRD4(IC50 = 22 nM)具有高度的亲和力。 了解更多