Epigenetic Reader Domain

Catalog No.Inhibitor Name Epigenetic Reader Domain
A12729(*)-JQ1
***
A11783I-BET151
*
A12545PFI-1
**
A11440I-BET-762
***
A13956RVX-208
*
A13227SGC-CBP30
****
A13163Bromosporine
****
A13890OTX015
****
A12948UNC1215
**
A13717UNC669
*
A14133GSK1324726A
***
A13749MS436
**
A13068CPI-203
***
A13957PFI-3

Notes:
1.Hover mouse over " * " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " * " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.

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  1. GSK 525762A (I-BET-762)

    Catalog No. A11440
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    BET 抑制剂
    GSK 525762A (I-BET-762)是BET(溴域和末端外)家族的小分子抑制剂。 了解更多
  2. (+)-JQ1

    Catalog No. A12729
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    BET 抑制剂
    (+)-JQ1是有效的,高亲和力的选择性BET溴结构域抑制剂。 了解更多
  3. BET-BAY 002

    Catalog No. A16368
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    BET 抑制剂
    BET-BAY 002是一种有效的BET抑制剂,对多发性骨髓瘤模型有效。 了解更多
  4. CPI 0610

    Catalog No. A16076
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    BET bromodomain 抑制剂
    CPI 0610是Bromodomain和Extra-Terminal(BET)蛋白家族的小分子抑制剂,具有潜在的抗肿瘤活性。 了解更多
  5. GW841819X

    Catalog No. A16367
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    BET 抑制剂
    GW841819X是(+)-JQ1的类似物,是BET溴结构域的新型抑制剂。GW841819X是单个对映异构体,但在苯并二氮杂3.环3的4位具有不确定的手性。 了解更多

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