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￥ 0.00 Topoisomerase
| Catalog No. | Inhibitor Name | Topoisomerase | Topo I | Topo II | Topo IV | Other |
|---|---|---|---|---|---|---|
| A10174 | Camptothecin | ** | ||||
| A10939 | Topotecan HCl | **** | ||||
| A10465 | Idarubicin HCl | *** | Multicellular spheroids | |||
| A10194 | Daunorubicin HCl | *** | ||||
| A11999 | Betulinic acid | ** | HIV-1,Aminopeptidase N | |||
| A11861 | Flumequine | * | ||||
| A14403 | Doxorubicin | |||||
| A10373 | Etoposide | |||||
| A10478 | Irinotecan | |||||
| A10345 | Epirubicin HCl | |||||
| A10596 | Mitoxantrone HCl | |||||
| A10609 | Moxifloxacin HCl | |||||
| A10479 | Irinotecan HCl Trihydrate | |||||
| A12011 | SN-38 | |||||
| A10071 | Amonafide | |||||
| A10907 | Teniposide | |||||
| A10419 | Gatifloxacin | |||||
| A10426 | Genistein | EGFR | ||||
| A10595 | Mitoxantrone | |||||
| A10735 | Pirarubicin | |||||
| A10041 | Adriamycin | |||||
| A10557 | Marbofloxacin | |||||
| A10666 | Ofloxacin | |||||
| A10740 | Podophyllotoxin | |||||
| A12663 | Amrubicin | |||||
| A13059 | Beta-Lapachone | IDO1 |
Notes:
1.Hover mouse over "" to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of "" is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.
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Flumequine
Catalog No. A11861 Topoisomerase II 抑制剂Flumequine是一种合成化学抗生素，可在回旋酶/拓扑异构酶水平上影响哺乳动物染色体和DNA的解链。抑制拓扑异构酶II， IC50为15 μM。 了解更多 -
Amrubicin
Catalog No. A12663 -
Gatifloxacin
Catalog No. A10419 DNA gyrase/topoisomerase IV 抑制剂Gatifloxacin是一种氟喹诺酮类抗生素，可抑制细菌dna回旋酶(IC50 = 0.109 ng/ml)和拓扑异构酶iv(IC50 = 13.8 ng/ml)。 了解更多 -
Ofloxacin (DL8280)
Catalog No. A10666 -
Ametantrone
Catalog No. A12569 topoisomerase II 抑制剂Ametantrone (AM)是一种合成的9,10-蒽二酮，在位置1和4上带有两个（羟乙基氨基）乙基氨基残基，以及其他蒽醌和蒽环类化合物。 了解更多 -
TAS 103 2HCl
Catalog No. A14141 -
Nemorubicin
Catalog No. A14363 Topoisomerase II 抑制剂Nemorubicin是一种抗癌药物，IC50值为0.08 uM。它对抗烷化剂，拓扑异构酶II抑制剂和铂衍生物具有抗性的肿瘤具有活性。它主要通过抑制拓扑异构酶I起作用。 了解更多
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