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￥ 0.00 FGFR
| Catalog No. | Inhibitor Name | FGFR | FGFR1 | FGFR2 | FGFR3 | FGFR4 | Other |
|---|---|---|---|---|---|---|---|
| A10080 | Ponatinib | **** | Abl,PDGFRα,VEGFR2 | ||||
| A11159 | BGJ398 | **** | **** | **** | ** | VEGFR2,Lyn,Kit | |
| A10137 | Nintedanib | ** | ** | ** | * | VEGFR3,VEGFR2,LCK | |
| A10703 | PD173074 | ** | VEGFR2,c-Src | ||||
| A11411 | Dovitinib | *** | *** | FLT3,c-Kit,VEGFR3/FLT4 | |||
| A11075 | AZD4547 | **** | **** | **** | * | KDR,IGFR | |
| A10715 | Danusertib | ** | Aurora A,Abl,TrkA | ||||
| A10953 | Orantinib | * | PDGFRβ,Flk1 | ||||
| A10254 | Brivanib | * | VEGFR2,Flk1,VEGFR1 | ||||
| A10198 | Dovitinib Dilactic Acid | *** | *** | FLT3,c-Kit,VEGFR3/FLT4 | |||
| A11753 | MK-2461 | ** | ** | ** | |||
| A10162 | Brivanib Alaninate | * | VEGFR2,Flk1,VEGFR1 | ||||
| A13211 | SSR128129E | * | VEGFR2,PDGFRβ | ||||
| A11558 | SU5402 | ** | |||||
| A15534 | BLU9931 | * | * | * | **** | ||
| A12357 | FIIN-2 | **** | *** | ** | ** | FLT3,c-Kit,VEGFR3/FLT4 | |
| A14415 | CH5183284 | *** | *** | *** | * | VEGFR2 | |
| A11244 | LY2874455 | **** | **** | *** | *** | ||
| A15957 | Erdafitinib | ||||||
| A10508 | KW-2449 | ** | FLT3, Bcr-Abl, Aurora A, PDGFRβ, IGF-1R, EGFR | ||||
| A10699 | Pazopanib HCl | * | VEGFR1, VEGFR2, VEGFR3, PDGFR, c-Kit, c-Fms | ||||
| A11518 | Pazopanib | * | VEGFR1, VEGFR2, VEGFR3, PDGFR, c-Kit, c-Fms | ||||
| A13111 | R 1530 | * | Chk2, KDR, FGFR, Aurora A, Cdk2, VEGFR-2, PDGFRβ | ||||
| A15073 | E-3810 | *** | ** | VEGFR1, VEGFR2, VEGFR3 | |||
| A15848 | FIIN-3 | *** | ** | ** | ** | ||
| A15957 | Alofanib (RPT835) |
Notes:
1.Hover mouse over "" to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of "" is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.
7 个项目
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Brivanib alaninate (BMS-582664)
Catalog No. A10162 -
Dovitinib Dilactic acid (TKI258 Dilactic acid)
Catalog No. A10198 RTK 抑制剂Dovitinib是一种小分子多靶点酪氨酸激酶抑制剂，可抑制通过ZNF198-FGFR1或BCR-FGFR1转化为IL3独立性的Ba / F3细胞，IC50值分别为150 nM和90 nM。 了解更多 -
Pazopanib (GW-786034)
Catalog No. A11518 VEGFR 抑制剂Pazopanib (GW-786034)是VEGFR-1，VEGFR-2，VEGFR-3，PDGFR-a/β和c-kit的有效且选择性的多靶点酪氨酸激酶抑制剂，可阻止肿瘤生长并抑制血管生成。 了解更多 -
Dovitinib (TKI-258)
Catalog No. A11411 RTK 抑制剂Dovitinib是一种小分子多靶点酪氨酸激酶抑制剂，可抑制通过ZNF198-FGFR1或BCR-FGFR1转化为IL3独立性的Ba / F3细胞，IC50值分别为150 nM和90 nM。 了解更多 -
Brivanib (BMS-540215)
Catalog No. A10254 VEGFR-2 抑制剂Brivanib (BMS-540215)是一种VEGFR-2抑制剂，IC50为25 nM，Ki为26 nM。 了解更多 -
Nintedanib esylate
Catalog No. A16197 RTK 抑制剂Nintedanib esylate是多种受体酪氨酸激酶（RTK）和非受体酪氨酸激酶（nRTK）的有效抑制剂。 了解更多
7 个项目
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