PDE
Catalog No. | Inhibitor Name | PDE | PDE1 | PDE2 | PDE3 | PDE4 | PDE5 | PDE6 | PDE9A | PDE10A | Other |
---|---|---|---|---|---|---|---|---|---|---|---|
A10804 | Roflumilast | **** | |||||||||
A10216 | Cilomilast | *** | |||||||||
A10883 | Tadalafil | *** | |||||||||
A10733 | Pimobendan | ** | |||||||||
A11073 | GSK256066 | **** | |||||||||
A11191 | PF-2545920 | **** | |||||||||
A10805 | Rolipram | ** | |||||||||
A10217 | Cilostazol | ** | |||||||||
A10592 | Milrinone | ** | ** | ATPase | |||||||
A12619 | Avanafil | **** | |||||||||
A10066 | Aminophylline | * | adenosine receptor | ||||||||
A15799 | TAK-063 | **** | |||||||||
A13722 | Deltarasin | *** | |||||||||
A10541 | Luteolin | * | * | * | * | * | |||||
A10464 | Icariin | ** | mAChR,AChR | ||||||||
A10480 | Irsogladine | ||||||||||
A10319 | Dipyridamole | ||||||||||
A10339 | Dyphylline | ||||||||||
A11527 | PF-8380 | *** | |||||||||
A10965 | Vardenafil | *** | **** | ||||||||
A11019 | Ibudilast (KC-404) | ||||||||||
A11289 | Apremilast (CC 10004) | *** | |||||||||
A11326 | Bay 60-7550 | **** | |||||||||
A11602 | Vinpocetine | Sodium channel | |||||||||
A12550 | Zardaverine | ** | ** | ||||||||
A12631 | Sildenafil | *** | *** | ||||||||
A12776 | AN2728 | *** | |||||||||
A13121 | PF-04447943 | *** | |||||||||
A13467 | MK-0359 | ||||||||||
A13596 | Cilostamide | *** | |||||||||
A15191 | Nortadalafil | ||||||||||
A15197 | Oglemilast | **** | |||||||||
A15198 | Olprinone Hydrochloride |
Notes:
1.Hover mouse over " " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.
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Aminophylline
Catalog No. A10066 Adenosine receptor 拮抗剂Aminophylline是一种非选择性的腺苷受体拮抗剂和磷酸二酯酶抑制剂,能够逆转局部缺血引起的bradyasystole。 了解更多 -
Dyphylline
Catalog No. A10339 Adenosine receptor 拮抗剂Dyphylline是黄嘌呤衍生物,具有支气管扩张药和血管扩张药的作用。 它充当腺苷受体拮抗剂和磷酸二酯酶抑制剂。 了解更多