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￥ 0.00 Aurora Kinase
| Catalog No. | Inhibitor Name | Aurora A | Aurora B | Aurora C | Other |
|---|---|---|---|---|---|
| A10004 | Alisertib | **** | * | ||
| A10981 | Tozasertib | **** | ** | *** | Bcr-Abl,FLT3 |
| A10109 | Barasertib | * | **** | ||
| A11009 | ZM 447439 | ** | * | LCK,Src,MEK1 | |
| A10601 | MLN8054 | **** | * | LCK,PKA,CK2 | |
| A10715 | Danusertib | *** | ** | ** | Abl,TrkA,RET |
| A10095 | AT9283 | **** | **** | JAK3,JAK2,Abl1 (T315I) | |
| A10494 | JNJ-7706621 | *** | *** | CDK2/CyclinE,CDK2/CyclinA,CDK1/CyclinB | |
| A10448 | Hesperadin | * | TbAUK1 | ||
| A10100 | Aurora A Inhibitor I | **** | * | * | |
| A10508 | KW-2449 | ** | FLT3 (D835Y),Abl (T315I),FLT3 | ||
| A10851 | SNS-314 Mesylate | *** | ** | **** | |
| A10352 | ENMD-2076 | *** | * | FLT3,RET,VEGFR3/FLT4 | |
| A10714 | PHA-680632 | ** | * | * | FGFR1,PLK1,FLT3 |
| A11410 | MK-5108 | **** | |||
| A10248 | CYC116 | *** | *** | VEGFR2,FLT3,CDK2/CyclinE | |
| A11066 | AMG-900 | *** | **** | **** | p38α,TYK2,JNK2 |
| A11171 | PF-03814735 | **** | *** | FLT1,FAK,TrkA | |
| A10184 | CCT129202 | ** | * | * | |
| A11168 | GSK1070916 | * | **** | *** | FLT1,Tie-2,SIK |
| A11067 | TAK-901 | ** | *** | JAK3,c-Src,YES1 | |
| A11081 | CCT137690 | *** | ** | ** | |
| A13396 | MK-8745 | **** | * | ||
| A10352 | ENMD-2076 L-(*)-Tartaric acid | *** | * | FLT3,RET,VEGFR3/FLT4 | |
| A15762 | BI-847325 | ** | **** | *** | |
| A13250 | Reversine | *** | *** | ** | human A3 adenosine receptor |
Notes:
1.Hover mouse over "" to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of "" is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.
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PF-03814735
Catalog No. A11171 Aurora A/B Kinase 抑制剂PF-03814735是一种新颖，有效且可逆的Aurora A/B抑制剂，IC50为0.8 nM/5 nM，对Flt3，FAK，TrkA的效力较低，对Met和FGFR1的活性最低。 了解更多
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