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￥ 0.00 VEGFR
| Catalog No. | Inhibitor Name | VEGFR1 | VEGFR2 | VEGFR3 | Other |
|---|---|---|---|---|---|
| A10001 | Sorafenib Tosylate | ** | Raf-1,B-Raf,B-Raf (V599E) | ||
| A10880 | Sunitinib Malate | * | Kit,FLT3,PDGFRβ | ||
| A10996 | Cabozantinib | *** | **** | *** | c-Met,Kit,Axl |
| A10080 | Ponatinib | **** | Abl,PDGFRα,FGFR1 | ||
| A10103 | Axitinib | **** | **** | **** | PDGFRβ,Kit,PDGFRα |
| A10998 | Foretinib | *** | **** | **** | Met,Tie-2,RON |
| A10963 | Vandetanib | ** | * | ||
| A10137 | Nintedanib | ** | *** | *** | LCK,FLT3,FGFR2 |
| A10250 | Regorafenib | *** | **** | * | RET,Raf-1,Kit |
| A11518 | Pazopanib HCl | *** | ** | * | FGFR,PDGFR,c-Kit |
| A10185 | Cediranib | *** | **** | **** | c-Kit,PDGFRβ,FGFR1 |
| A10703 | PD173074 | * | FGFR1,c-Src | ||
| A11411 | Dovitinib | *** | *** | *** | FLT3,c-Kit,FGFR1 |
| A10025 | Linifanib | **** | **** | * | CSF-1R,FLT3,Kit |
| A10967 | Vatalanib 2HCl | * | ** | * | PDGFRβ,c-Kit,c-Fms |
| A10773 | RAF265 | ** | B-Raf | ||
| A10101 | Tivozanib | ** | *** | ** | EphB2,PDGFRα,PDGFRβ |
| A10608 | Motesanib Diphosphate | **** | **** | *** | Kit,RET,PDGFR |
| A10340 | Lenvatinib | ** | **** | *** | PDGFRβ,FGFR1,PDGFRα |
| A10953 | Orantinib | * | PDGFRβ,FGFR1 | ||
| A10254 | Brivanib | * | ** | FGFR1 | |
| A10587 | MGCD-265 | **** | **** | **** | Met,RON,Tie-2 |
| A10043 | AEE788 | * | * | * | EGFR,HER2/ErbB2,c-Abl |
| A10352 | ENMD-2076 | * | ** | FLT3,RET,Aurora A | |
| A10679 | OSI-930 | *** | *** | CSF-1R,LCK,C-Raf | |
| A10248 | CYC116 | ** | Aurora A,Aurora B,FLT3 | ||
| A10502 | Ki8751 | **** | c-Kit,PDGFRα,FGFR2 | ||
| A10903 | Telatinib | *** | **** | c-Kit,PDGFRα | |
| A11518 | Pazopanib | *** | ** | * | FGFR,PDGFR,c-Kit |
| A10504 | KRN 633 | * | * | * | PDGFRα,c-Kit,BTK |
| A13377 | SAR131675 | ** | |||
| A10198 | Dovitinib Dilactic Acid | *** | *** | *** | FLT3,c-Kit,FGFR1 |
| A11407 | Apatinib | **** | RET,c-Kit,c-Src | ||
| A10154 | BMS-794833 | ** | Met | ||
| A10162 | Brivanib Alaninate | * | ** | FGFR1 | |
| A11396 | Golvatinib | ** | c-Met | ||
| A11954 | ZM 323881 HCl | **** | |||
| A11955 | ZM 306416 | * | Src,Abl | ||
| A16342 | BFH772 | **** | |||
| A11558 | SU5402 | ** | FGFR1,PDGFRβ | ||
| A12437 | Semaxanib | * | |||
| A11244 | LY2874455 | *** | FGFR2,FGFR1,FGFR4 | ||
| A13234 | SKLB1002 | ** | |||
| A14156 | AZD2932 | *** | PDGFRβ,Flt3,c-Kit | ||
| A10893 | Taxifolin (Dihydroquercetin) | ||||
| A11772 | CP-547632 | *** | FGFR | ||
| A12693 | BAW2881 (NVP-BAW2881) | * | *** | * | C-Raf-1,B-RAFV599E,c-Abl |
| A13465 | SKLB610 | * | PDGFR, FGFR2 | ||
| A13819 | TG 100801 | **** | *** | FGFR1, Fyn, Src | |
| A13820 | TG 100572 | **** | *** | FGFR1, Fyn, Src | |
| A14387 | ltiratinib (DCC2701) | *** | MET, TIE2, TRK | ||
| A15073 | E-3810 | *** | ** | *** | FGFR-1, FGFR-2 |
| A15287 | ZM323881 | **** | |||
| A15792 | BMS-817378 | *** | c-Met |
Notes:
1.Hover mouse over "" to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of "" is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.
23 个项目
每页
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Dovitinib (TKI-258)
Catalog No. A11411 RTK 抑制剂Dovitinib是一种小分子多靶点酪氨酸激酶抑制剂，可抑制通过ZNF198-FGFR1或BCR-FGFR1转化为IL3独立性的Ba / F3细胞，IC50值分别为150 nM和90 nM。 了解更多 -
Nintedanib esylate
Catalog No. A16197 RTK 抑制剂Nintedanib esylate是多种受体酪氨酸激酶（RTK）和非受体酪氨酸激酶（nRTK）的有效抑制剂。 了解更多 -
Brivanib (BMS-540215)
Catalog No. A10254 VEGFR-2 抑制剂Brivanib (BMS-540215)是一种VEGFR-2抑制剂，IC50为25 nM，Ki为26 nM。 了解更多 -
N-Desethyl Sunitinib
Catalog No. A15182 VEGFR/PDGFRβ/KIT 抑制剂N-Desethyl Sunitinib是舒尼替尼的主要药理活性代谢产物，是有效的，ATP竞争性VEGFR，PDGFRβ和KIT抑制剂（VEGFR -1，-2，-3的Ki值为2、9、17、8和4 nM。分别为PDGFRβ和KIT）。 了解更多 -
Regorafenib (BAY 73-4506)
Catalog No. A10250 VEGFR 抑制剂Regorafenib (BAY 73-4506)是一种多激酶抑制剂，IC50为17、40和69 nM c-KIT，VEGFR2，B-Raf。Regorafenib（BAY 73-4506）是一种针对肿瘤及其脉管系统的口服生物利用型多激酶抑制剂。 了解更多 -
Pazopanib (GW-786034)
Catalog No. A11518 VEGFR 抑制剂Pazopanib (GW-786034)是VEGFR-1，VEGFR-2，VEGFR-3，PDGFR-a/β和c-kit的有效且选择性的多靶点酪氨酸激酶抑制剂，可阻止肿瘤生长并抑制血管生成。 了解更多 -
NVP-BAW2881
Catalog No. A12693 VEGFR 抑制剂NVP-BAW2881是有效的选择性VEGFR抑制剂（血管内皮生长因子受体酪氨酸激酶抑制剂），IC50 为值9 nM，具有抑制慢性和急性皮肤炎症的作用。 了解更多 -
CYC116 (CYC-116)
Catalog No. A10248 Aurora Kinase 抑制剂CYC116 (CYC-116)是一种有效的Aurora A/B抑制剂，Ki为8.0 nM/9.2 nM，对VEGFR2(Ki为44 nM)作用稍弱。 了解更多 -
Regorafenib monohydrate
Catalog No. A15218 Tyrosine kinase 抑制剂Regorafenib monohydrate是VEGFR1/VEGFR2/VEGFR3/PDGFRβ/Kit/RET和Raf-1的多靶点抑制剂，IC50分别为13 nM/4.2 nM/46 nM/22 nM/7 nM/1.5 nM和2.5 nM。 了解更多 -
Raf265 derivative
Catalog No. A10774 RAF/VEGFR 抑制剂Raf265 derivative是Raf265的衍生物，Raf265是一种口服，高度选择性的RAF和VEGFR激酶抑制剂，IC50为5至10μM。 了解更多 -
LY 2874455
Catalog No. A11244 -
Vandetanib trifluoroacetate
Catalog No. A15272 -
RAF265 (CHIR-265)
Catalog No. A10773 RAF/VEGFR 抑制剂RAF265 (CHIR-265)是一种口服，高度选择性的RAF和VEGFR激酶抑制剂，可控制或正常化VEGFR-2，同时抑制B-raf和c-Raf突变以预防癌症。 了解更多 -
Dovitinib Dilactic acid (TKI258 Dilactic acid)
Catalog No. A10198 RTK 抑制剂Dovitinib是一种小分子多靶点酪氨酸激酶抑制剂，可抑制通过ZNF198-FGFR1或BCR-FGFR1转化为IL3独立性的Ba / F3细胞，IC50值分别为150 nM和90 nM。 了解更多 -
BFH772
Catalog No. A16342 -
Brivanib alaninate (BMS-582664)
Catalog No. A10162
23 个项目
每页