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￥ 0.00 mTOR
| Catalog No. | Inhibitor Name | mTOR | mTORC1 | mTORC2 | Other Targets |
|---|---|---|---|---|---|
| A10133 | Dactolisib | *** | p110α,p110γ,p110δ | ||
| A10782 | Rapamycin | **** | |||
| A10374 | Everolimus | *** | |||
| A10114 | AZD8055 | **** | DNA-PK,PI3Kδ,PI3Kα | ||
| A10906 | Temsirolimus | * | |||
| A10726 | PI-103 | * | p110α,p110δ,p110β | ||
| A10505 | KU-0063794 | ** | ** | ||
| A10746 | Torkinib | ** | p110δ,PDGFR,DNA-PK | ||
| A10295 | Ridaforolimus | **** | |||
| A11461 | INK 128 | **** | PI3Kα,PI3Kγ,PI3Kδ | ||
| A10997 | Voxtalisib Analogue | * | PI3Kγ,PI3Kα,PI3Kδ | ||
| A11587 | Torin 1 | *** | *** | ** | DNA-PK,p110γ,C2α |
| A11035 | Omipalisib | **** | **** | p110α,p110δ,p110γ | |
| A11056 | OSI-027 | *** | * | * | PI3Kγ,DNA-PK,PI3Kα |
| A11024 | PF-04691502 | ** | PI3Kδ,PI3Kα,PI3Kγ | ||
| A11023 | Apitolisib | * | p110α,p110δ,p110γ | ||
| A10438 | GSK1059615 | ** | PI3Kα,PI3Kβ,PI3Kδ | ||
| A11079 | Gedatolisib | **** | PI3Kα,PI3Kγ | ||
| A10989 | WYE-354 | *** | PI3Kα,PI3Kγ | ||
| A11303 | Vistusertib | *** | P-Akt (S473),pS6 (S235/236) | ||
| A11586 | Torin 2 | **** | ATM,ATR,DNA-PK | ||
| A11038 | WYE-125132 | **** | |||
| A11207 | PP121 | ** | PDGFR,Hck,VEGFR | ||
| A11187 | WYE-687 | *** | PI3Kα,PI3Kγ,p38α | ||
| A11169 | CH5132799 | * | PI3Kα,PI3Kγ,PI3Kβ | ||
| A11188 | WAY-600 | ** | PI3Kα,PI3Kγ | ||
| A13328 | ETP-46464 | **** | ATR,DNA-PK,PI3Kα | ||
| A11443 | GDC-0349 | *** | PI3Kα | ||
| A12395 | XL388 | ** | ** | * | CYP2C9,CYP3A4 |
| A13078 | CC-223 | ** | cFMS,FLT4,DNA-PK | ||
| A16276 | Voxtalisib | * | PI3Kγ,PI3Kα,PI3Kδ | ||
| A11950 | Zotarolimus | *** | |||
| A10389 | Tacrolimus | ||||
| A11162 | BGT226 | PI3Kα,PI3Kγ,PI3Kβ | |||
| A10693 | Palomid 529 | ||||
| A10210 | Chrysophanic Acid | EGFR | |||
| A11537 | QL-IX-55 | ||||
| A12480 | VS-5584 | **** | PI3Kα, PI3Kδ, PI3Kγ, PI3Kβ | ||
| A12704 | SF1126 | PI3K | |||
| A12935 | PF-04979064 | **** | PI3Kα, PI3Kδ, PI3Kγ, PI3Kβ, Akt | ||
| A14432 | GNE-493 | *** | PI3Kα, PI3Kδ, PI3Kγ, PI3Kβ | ||
| A15175 | mTOR inhibitor (mTOR-IN-1) | *** | |||
| A15508 | MHY1485 | ||||
| A16126 | LY3023414 | PI3Kα, Akt1, DNA-PK |
Notes:
1.Hover mouse over "" to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of "" is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.
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XL388
Catalog No. A12395 -
ETP-46464
Catalog No. A13328 -
PF-04979064
Catalog No. A12935